Results 61 to 70 of about 2,898,245 (291)
Social networking and transnational capitalism [PDF]
, 2011 Social Networking Sites (SNS) have become a key component of users’ experience of the internet. Whilst much has been made of the social dynamics of online SNS, the influence of the structures and operations of these sites – and the business models behind
Kreps, DGP
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The surge in living alone among young and middle-aged adults: A decomposition analysis of the rise in one-person households in Germany, 1991 to 2021 [PDF]
Demographic ResearchBACKGROUND: Worldwide, the number of people living in a one-person household (OPH) is rising, and young and middle-aged adults play an essential role in this trend. Germany has one of Europe’s highest rates of OPHs.
Anne-Sophie Oehrlein, Christof Wolf
doaj +1 more source
The institutional character of computerized information systems [PDF]
, 1989 We examine how important social and technical choices become part of the history of a computer-based information system (CB/SJ and embedded in the social structure which supports its development and use.
Iacono, Suzanne, Kling, Rob
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Matemáticas sociales y estructuras del liberalismo: teoría de juegos e hipergrafos
Revista Integración, 2012 Se recuerdan algunos resultados de las matemáticas sociales que se han orientado en el liberalismo, económico y político, que nos legó el siglo XVIII.
Andreas Polyméris
doaj
Feudalism in early medieval Kashmir
Cogent Arts & HumanitiesThe study attempts to analyse the nature of feudalism in Early Medieval Kashmir, presenting an exploration of its social and political dynamics. Contrary to typical European feudal models, Kashmir’s feudal system was characterised by a unique interplay ...
Rashid Manzoor Bhat
doaj +1 more source
Social Structures for Learning [PDF]
This article investigates what learning groups there are in organizations, other than the familiar 'communities of practice'. It first develops an interdisciplinary theoretical framework for identifying, categorizing and understanding learning groups ...
Bogenrieder, I.M., Nooteboom, B.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source