Results 81 to 90 of about 2,898,245 (291)
Minding the Gap: Bias, Soft Structures, and the Double Life of Social Norms [PDF]
, 2018 We argue that work on norms provides a way to move beyond debates between proponents of individualist and structuralist approaches to bias, oppression, and injustice. We briefly map out the geography of that debate before presenting Charlotte Witt’s view,
Davidson, Lacey J., Kelly, Daniel
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Family policies in the context of low fertility and social structure
Demographic Research, 2013 Objective: In this paper we investigate the effectiveness of family policies in the context of the socialstructure of a population. Methods: We use an agent-based model to analyse the impact of policies on individual fertility decisions and on fertility ...
Belinda Aparicio Diaz +2 more
doaj
Social Structures for Learning [PDF]
, 2001 This article investigates what learning groups there are in organizations, other than the familiar 'communities of practice'. It first develops an interdisciplinary theoretical framework for identifying, categorizing and understanding learning groups ...
Bogenrieder, I.M. (Irma) +1 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Economy and Sociology, 2019 The aim of this study is clustering of administrative-territorial units of Ukraine on the basis of value orientations and the electoral choice of the population of these units. The k-means method is used.
Uliana LESHENOK
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Social Structures and Global Public Health Ethics
Journal of Moral Theology, 2021 The author relies on critical realist social theory because it provides an account of social reality that enables global public health ethicists to understand the causal mechanisms that perpetuate the suffering of the poor.
Daniel Daly
doaj
Langages structurés et lien social
Tic & Société, 2010 In this article, the authors propose a critical approach to interactivity through the use of markup languages and application frameworks. For twenty years, these languages have been reorganizing how interactivity is laid out in the development of ...
Alain Vaucelle, Henri Hudrisier
doaj +1 more source