Results 221 to 230 of about 56,234,534 (390)

Two Studies on the Interplay between Social Preferences and Individual Biological Features [PDF]

, 2013
Sanchez-Pages, Santiago, Turiegano, E.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Linear and curvilinear associations between affinity for solitude and adjustment in adolescence. [PDF]

J Res Adolesc
Zhou J, Chen X, Li D, Liu J, Zhou T.
europepmc   +1 more source

‘A lot of friends. A lot of appreciation and a phone that never stops ringing’: Voluntary action and social exclusion in East London - a pilot study [PDF]

, 2000
Michael Locke, Alice Sampson, Julie Shepherd   +2 more
openalex  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Operationalising social transition in trans and gender diverse youth: a scoping review of definitions and measures. [PDF]

EClinicalMedicine
Conabere W, Lami F, Andrews H, Skarlatos M, Pace CC, Buckingham P, Hay S, De Ieso T, Pang KC, Tollit MA.   +9 more
europepmc   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Sustainable assessment in digital health interventions for primary care: A scoping review. [PDF]

J Public Health Res
Alvarez-Rodríguez J, Fotis T, Tomsett B, Baid H.   +3 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Efficiency of Using Theatrical Method in Teaching Social Studies at Sixth Grade, Basic Education in the Sultanate of Oman and its Effects on Achievement and Subject Orientation [PDF]

, 2011
Saud S. AL-Nabhani
openalex   +1 more source