Results 121 to 130 of about 19,035,680 (291)

The Role of Social Comparison and Online Social Support in Social Media Addiction Mediated by Self-Esteem and Loneliness

open access: yesEuropean Journal of Mental Health
Introduction: The diversity of information on social media provides a ubiquitous possibility for social comparison. Online social comparisons have both detrimental and beneficial effects; besides lowering one’s self-esteem, heightening loneliness and ...
Bettina F. PIKÓ   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Gender differences in prolonged grief: a network perspective on symptom interconnections and functional impairment

open access: yesEuropean Journal of Psychotraumatology
Background: While prior studies have reported gender differences in prolonged grief symptom severity, less is known about symptom interconnections and their associations with functional impairment.
Yanjuan Li   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Human rights in pandemics: criminal and punitive approaches to COVID-19

open access: yesBMJ Global Health, 2022
Joseph J Amon   +3 more
doaj   +1 more source

Social Support

open access: yes, 2020
First paragraph: Flick through any autobiography of a celebrated athlete and you will find that one of its key themes is social support. Certainly there will be discussions of training and tactics, distress and disappointment, guts and glory. But the backdrop to all this is likely to be the support the athlete received from key individuals and groups ...
Hartley, Chris   +3 more
openaire  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

LECTURER’S PERSONALITY AS A MODEL OF PROFESSIONAL FORMATION OF STUDENT’S PERSONALITY

open access: yesВестник Кемеровского государственного университета, 2014
The paper presents the results of a research of the impact of lecturer’s personality on professional development of future railwaymen and lecturers. It opens and justifies as exemplified by modern research the role of the lecturer’s personality not only ...
M. V. Sokolskaya, O. O. Olifer
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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