Results 101 to 110 of about 7,992,011 (288)

AGENT: Alumni growth and engagement across new technologies [PDF]

open access: yes, 2012
The AGENT project aims to use social networking technologies (LinkedIn and Facebook) to support the development of undergraduates’ employability and career development.
Coughlan, J, Jamal, A, Macredie, RD
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Social Support Networks Among Children with Intellectual and Developmental Disabilities [PDF]

open access: yes, 2015
Previous research using predominantly adult populations has found that social support is positively correlated with an individual’s quality of overall health and wellbeing.
Hapke, Laura
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Case Studies on Elderly and Institutionalization in the Southern region of Kerala [PDF]

open access: yesJournal of Social Work Education and Practice, 2018
Aging is a period of decline and social attitude towards old age affects the aged population. The practice of institutionalizing the elderly is a broad spreading concept in the modern world, and the old age homes and hospices are growing day by day.
Sharon Fernandez   +2 more
doaj  

Social Justice Through the Lens of the Cross: A Case for a Biblical Foundation of Social Work [PDF]

open access: yes, 2019
Social work values social justice, as the profession promotes the well-being of society and the rights each person holds. Although social justice is a core value of social work, it is necessary to address the value’s foundation, and questioning the “why”
Kasch, Allison P
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Making Change: How Social Movements Work and How to Support Them [PDF]

open access: yes, 2009
Provides guidance for funders and activists on funding and sustaining a successful social movement. Details key elements of success, organizational capacities that need to be developed, areas for effective foundation investment, and issues to ...
Manuel Pastor, Rhonda Ortiz
core  

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