Results 91 to 100 of about 19,035,680 (291)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Tis Better to Give and to Receive: Social Support, Stress, and Mental Health in Dyadic Relationships

, 2019
Research Questions: How do levels of perceived support within dyadic social networks interact to predict mental health outcomes for both network members?
Hansard, Stephanie
core   +1 more source

Social support and the likelihood of maintaining and improving levels of physical activity:the Whitehall II Study [PDF]

, 2011
Background: Evidence on the association between social support and leisure time physical activity (LTPA) is scarce and mostly based on cross-sectional data with different types of social support collapsed into a single index. The aim of this study was to
Singh-Manoux, Archana, R. De Vogli, Kivimäki, Mika, Kouvonen, Anne, Shipley, M.J., T. Cox, De Vogli, Roberto, Kivimaki, M., T. Heponiemi, Marmot, M.G., Cox, Tom, Singh-Manoux, A., M. Stafford, Heponiemi, T., A. Kouvonen, Marmot, Michael G., J. Vahtera, Shipley, Martin J., Shipley, Martin, J., Marmot, Michael G, Vahtera, Jussi, Marmot, Michael, G., M. Kivimaki, Väänänen, Ari, de Vogli, R., Stafford, M., Väänänen, A., Shipley, Martin J, A. Singh-Manoux, M. G. Marmot, Stafford, Mai, Kouvonen, A., Vahtera, J., A. Vaananen, M. J. Shipley, Heponiemi, Tarja, Singh Manoux, Archana   +36 more
core   +1 more source

Transforming Development with Grassroots Planning in Madhya Pradesh, India

Commonwealth Journal of Local Governance, 2012
There is growing acknowledgment that state interactions must take place in a democratic context. This has been accompanied by attempts to foster forms of democratic governance that provide scope for citizen participation in the development process ...
Yogesh Mahor, Ram Gopal Singh
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Psychological rehabilitation of women with breast diseases: dynamics of quality of life before and after a psychotherapeutic program

Frontiers in Psychology
Breast cancer remains the most prevalent malignant neoplasm among women and is one of the leading causes of cancer-related mortality. Surgical interventions (particularly mastectomy), chemotherapy, and radiotherapy are frequently associated with ...
Aliya Uteulova, Ayazhan Janbayeva, Marat Assimov, Tatyana Vasko, Sanzhar Ismailov   +4 more
doaj   +1 more source

Dysfunctional Social Support: Delivering Social Support at Work in an Unappreciative Way

Occupational Health Science
Abstract Self-esteem, both personal and social, constitutes a core concern for many people. Accordingly, Stress-as-Offense-to-Self theory focuses on threats, as well as boosts, to the self as important topics in occupational health science. Workplace social support is well established as a resource that signals acceptance and appreciation. At
Semmer, Norbert K., Kälin, Wolfgang, Amstad, Fabienne T., Tschan, Franziska, Jacobshagen, Nicola, Beehr, Terry A., Lehmann, Mara, Elfering, Achim   +7 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Participation Questionnaire for Preschoolers With Autism Spectrum Disorder: Item Development

Occupational Therapy International
Occupational therapists need to comprehensively assess the participation of children with autism spectrum disorder (ASD) in daily activities and evaluate the effectiveness of relevant interventions.
Takuto Nakamura, Sakumi Koyama, Hirofumi Nagayama, Satoshi Sasada   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source