Results 71 to 80 of about 1,901,785 (266)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Educating Students with Autism Spectrum Disorders: Organizational Problems

Психологическая наука и образование, 2016
The article presents data of applied socio-psychological research devoted to the study of difficulties encountered by educational institutions when teaching children with autism spectrum disorders (ASD).
Samsonova E.,, Alekseeva M.N.,
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Psychological rehabilitation of women with breast diseases: dynamics of quality of life before and after a psychotherapeutic program

Frontiers in Psychology
Breast cancer remains the most prevalent malignant neoplasm among women and is one of the leading causes of cancer-related mortality. Surgical interventions (particularly mastectomy), chemotherapy, and radiotherapy are frequently associated with ...
Aliya Uteulova, Ayazhan Janbayeva, Marat Assimov, Tatyana Vasko, Sanzhar Ismailov   +4 more
doaj   +1 more source

Transforming Development with Grassroots Planning in Madhya Pradesh, India

Commonwealth Journal of Local Governance, 2012
There is growing acknowledgment that state interactions must take place in a democratic context. This has been accompanied by attempts to foster forms of democratic governance that provide scope for citizen participation in the development process ...
Yogesh Mahor, Ram Gopal Singh
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Participation Questionnaire for Preschoolers With Autism Spectrum Disorder: Item Development

Occupational Therapy International
Occupational therapists need to comprehensively assess the participation of children with autism spectrum disorder (ASD) in daily activities and evaluate the effectiveness of relevant interventions.
Takuto Nakamura, Sakumi Koyama, Hirofumi Nagayama, Satoshi Sasada   +3 more
doaj   +1 more source

Dysfunctional Social Support: Delivering Social Support at Work in an Unappreciative Way

Occupational Health Science
Abstract Self-esteem, both personal and social, constitutes a core concern for many people. Accordingly, Stress-as-Offense-to-Self theory focuses on threats, as well as boosts, to the self as important topics in occupational health science. Workplace social support is well established as a resource that signals acceptance and appreciation. At
Semmer, Norbert K., Kälin, Wolfgang, Amstad, Fabienne T., Tschan, Franziska, Jacobshagen, Nicola, Beehr, Terry A., Lehmann, Mara, Elfering, Achim   +7 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source