Results 151 to 160 of about 12,133,489 (310)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Teaching the YouTube generation: exploring the benefits of an interactive teaching approach in sustainable product design [PDF]
, 2014 This paper presents findings from a doctoral study, which investigated effective methods for teaching social sustainability within product design courses in British and Irish universities. Specifically exploring, how to foster a holistic understanding of
Watkins, MA
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Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Trees, Forests and PeopleAround the world, restoration activities are underway to halt and reverse ecosystem degradation. A key challenge is to identify restoration approaches that work for both people and nature – i.e.
Tom Reckmann +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Growing Smarter: Achieving Sustainability in Emerging Community Foundations [PDF]
, 2007 It's a striking paradox: as community foundations grow their assets, their sustainability is often threatened. That's the conclusion of a new paper written by FSG Social Impact Advisors and sponsored by The James Irvine Foundation.
Eva Nico +3 more
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Building climate resilience, social sustainability and equity in global fisheries. [PDF]
NPJ Ocean Sustain, 2023 Prellezo R +4 more
europepmc +1 more source
Public policies, environmental health, sustainability and social inclusion in developed countries [PDF]
, 2006 The paper discusses the range of public policies, concerned with environment health, sustainability and social inclusion, recently introduced by governments in developed ...
Lethbridge, Jane
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