Results 161 to 170 of about 12,133,489 (310)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Sherlock in OSS: A Novel Approach of Content-Based Searching in Object Storage System

open access: yesIEEE Access
Cloud-based Object Storage Systems (OSS) are known for their scalability, durability, availability, and concurrency. However, there is a noticable vaccum in open-source OSS for a straightforward way for users and administrators to conduct data searches ...
Jannatun Noor   +6 more
doaj   +1 more source

Getting Local: How Nonprofit News Ventures Seek Sustainability [PDF]

open access: yes, 2011
Examines eight nonprofit news ventures' mission, audience, reach, and social impact; revenue generation and diversification; and organizational adaptability, innovation, and resource allocation as critical elements of long-term ...

core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Social Sustainability of a Firm: Orientation, Practices, and Performances. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Wang X, Yang M, Park K, Um KH, Kang M.
europepmc   +1 more source

The Sustainable Approach to Corporate Social Responsibility: A Global Analysis and Future Trends [PDF]

open access: yes, 2019
Due to the process of globalization, companies are obligated to observe corporate social responsibility and best practices from a sustainability approach towards their stakeholders and society.
Abad Segura, Emilio   +2 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Sustainability and corporate governance: A comparative evaluation of approach for Dangote Group and Gallagher Group [PDF]

open access: yes, 2018
Sustainability has been resonating within the business community and the academia. Indeed, sustainability has moved from being an ideology to a technique that guarantees business profitability.
Okoro, Ogechi
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

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