Results 171 to 180 of about 20,876,453 (293)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Penn, Social Systems, and the Community: fostering equity-focused public health practice through asynchronous learning. [PDF]

Front Public Health
Stief A, Weigelt E, Greenidge K, Rosado N, Hall M, Aysola J, Nelson HCM.   +6 more
europepmc   +1 more source

Impact of individual actions on the collective response of social systems. [PDF]

Sci Rep, 2020
Martin-Gutierrez S, Losada JC, Benito RM.   +2 more
europepmc   +1 more source

The COVID-19 pandemic effects on the hospitality industry using social systems theory: A multi-country comparison. [PDF]

Int J Hosp Manag, 2021
Shapoval V, Hägglund P, Pizam A, Abraham V, Carlbäck M, Nygren T, Smith RM.   +6 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Air Force Systems Command Technical Documentary Report 61-453

, 1961
Report discussing a study initiated to investigate and apply techniques of microminiaturization to circuits designed for high reliability performance with two goals: (1) to develop ultra-reliability design techniques in communication equipment, and (2 ...
Anderson, George, Sylvania Electric Systems   +1 more
core  

Towards Health Policy for All-Re-visioning Health and Social Systems for Equity and Resilience. [PDF]

Acta Med Philipp
Estacio LR, Pasco PM.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A quantum-driven multi-objective scheduler for scalable task orchestration in fog-based cyber-physical-social systems. [PDF]

Sci Rep
Hammouda NG, Shalaby M, Alfilh RHC, Singh NSS.   +3 more
europepmc   +1 more source

Epigenomics and gene regulation in mammalian social systems. [PDF]

Curr Zool, 2020
Guerrero TP, Fickel J, Benhaiem S, Weyrich A.   +3 more
europepmc   +1 more source