Results 231 to 240 of about 2,869,935 (306)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Dopamine, Distraction, and Disruption: Perspectives on How Technology and Generation Z Are Reshaping Medical Education.

JMIR Med Educ
Andrade BB, Araújo Pereira M, Avena K.
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Centring Social Justice in Nursing Educational Resources: Equity, Diversity, and Inclusion. [PDF]

Can J Nurs Res
Lapum JL, St-Amant O, Hughes M, Garmaise-Yee J.   +3 more
europepmc   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Effect of early clinical exposure based health systems science course in the Korean medical education: a prospective observational study. [PDF]

BMC Med Educ
Lee HY, Im S, Shin SW, Kim JA, Song JM.
europepmc   +1 more source

Examining the role of social support and death anxiety on life expectancy among cancer patients. [PDF]

J Educ Health Promot
Manzour R, Haj Hashemi F, Ghaedi-Heidari F, Taheri Z.   +3 more
europepmc   +1 more source

Building Leadership Capacity Through Systems Thinking: Principles and Habits for Educators. [PDF]

New Dir Stud Leadersh
Niewoehner-Green JE, Hogan D, Sedar A.
europepmc   +1 more source

Designing a flipped AI-chatbot learning module to support students' environmental literacy development: A Fuzzy Delphi Method. [PDF]

PLoS One
Wang X, Li X.
europepmc   +1 more source

Adaptive actions and treatment outcomes in transdiagnostic internet-delivered cognitive behaviour therapy for chronic health conditions. [PDF]

Internet Interv
Hadjistavropoulos HD, Peynenburg V, Philipp-Muller AE, Nomeikaite A, Titov N, Dear BF, Staples L.   +6 more
europepmc   +1 more source