Results 81 to 90 of about 2,869,935 (306)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Community coalitions’ navigation of policies to address the opioid epidemic: insights from qualitative interviews in four states

BMJ Public Health
Introduction The opioid epidemic in the USA presents a multifaceted challenge regulated by a patchwork of federal, state and local policies. In some communities, cross-sector coalitions navigate this complex policy environment to address the epidemic ...
Elizabeth N Kinnard, Ann Scheck McAlearney, Timothy Hunt, Ramona G Olvera, Allyson G Cogan, Mary Bartkus, Shoshana N Benjamin, Jill Davis, Lisa A Frazier, Brandy F Henry, Hallie Mattingly, Dean Rivera, Mari-Lynn Drainoni, Daniel M Walker   +13 more
doaj   +1 more source

Social Media and Entrepreneurial Thinking: The Mediating Role of Motivation among University Students [PDF]

Management and Economics Review
This study examines how social media relates to entrepreneurial thinking among university students and clarifies the role of motivation using established psychological frameworks.
Lotfi MEKHZOUMI, Akram BAKADI, Imad BELLOUL   +2 more
doaj   +1 more source

Thinking in Chinese vs. Thinking in English: Social Preference and Risk Attitudes of Multicultural Minds [PDF]

This paper investigates whether language priming activates different cultural identities and norms associated with the language communicated with respect to social preference and risk attitudes.
Li King King
core  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Does reflective supervision have a future in English local authority child and family social work? [PDF]

, 2017
Purpose – (1) to discuss the underlying assumption that social workers need reflective supervision specifically, as opposed to managerial or any other form of supervision or support; and (2) to consider whether our focus on the provision of reflective ...
Wilkins, David
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Social thinking is for doing: the posterior cerebellum supports predictions of social actions based on personality traits. [PDF]

Soc Cogn Affect Neurosci, 2022
Haihambo N, Ma Q, Baeken C, Deroost N, Baetens K, Heleven E, Overwalle FV.   +6 more
europepmc   +1 more source

Social Entrepreneurship Collaboratory: (SE Lab): A University Incubator for a Rising Generation of Leading Social Entrepreneurs [PDF]

, 2006
How can universities help create, develop and sustain a rising generation of social entrepreneurs and their ideas? What new forms of learning environments successfully integrate theory and practice?
Gordon Bloom
core  

Design thinking and innovation: synthesising concepts of knowledge co-creation in spaces of professional development [PDF]

, 2016
This paper explores how design thinking connects to concepts of knowledge creation and innovation. A case study of a knowledge sharing network in the social services sector is used to illustrate how design thinking supports Ba, the spaces for knowledge ...
Davis, John, Docherty, Catherine Ann, Dowling, Kate   +2 more
core   +4 more sources