Results 61 to 70 of about 3,635,145 (314)
High culture outside the City: introduction
Историческая этнология, 2022 The introductory article to the thematic issue “High Culture Outside the City: Intellectual Environment, Education and Entrepreneurship” provides a brief overview of articles covering the following topics: 1) the activities of the Izh-Buby madrasah, its ...
Dinara Z. Mardanova +1 more
doaj
Social Work, Power and Performativity [PDF]
, 2012 In recent years, there have been a number of epistemological developments in social work. Further, there have been a number of theoretical approaches that have attempted to ground the concept of ‘power’ to understand organizational practice such as ...
Powell, Jason
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Grantees' Limited Engagement with Foundations' Social Media [PDF]
, 2012 It is not surprising that foundations are investing in social media tools. These tools can serve myriad functions for foundations, from promoting a culture of transparency to the public at large, to influencing thought leaders, to connecting with ...
Andrea Brock, Ellie Buteau
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Next Generation Evaluation: Embracing Complexity, Connectivity, and Change [PDF]
, 2013 This Learning Brief draws from literature and research, as well as more than a dozen interviews with foundation leaders, evaluation practitioners, and social sector thought leaders, with the intention of starting the conversation in the field around Next
Hallie Preskill, Shijie Lu, Srik Gopal
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tempo Social, 1999 Os estudos de relações raciais realizados no Brasil entre 1937 e 1956 são muitas vezes invocados para respaldar a opinião de que existem diferenças regionais na situação racial brasileira ou de que diferentes escolas regionais interpretaram ...
Antônio Sérgio Alfredo Guimarães
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source