Results 91 to 100 of about 26,978,530 (253)
TIME IN PROFESSORS’ LIVES THROUGH THE EYES OF SOCIOLOGISTS
The authors analyze the results of a qualitative study of the temporal behaviour strategies of representatives of the research pedagogical and scientific community, investigate the temporal behaviour strategies in the context of cognitive, emotional and ...
Polina A. Ambarova, Garold E. Zborovsky
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Prime Time, No. 13 (February, 1980)
The object of Prime Time was to gather information about issues, needs and concerns of women in their middle years. It was co-sponsored by the B.C.
British Columbia Association of Social Workers
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
NEW STYLE OF THE CULTURAL HERITAGE
The paper analyzes the characteristics of the broadcast of sociocultural experience. It is shown that modern historical stage is associated with the formation of a united democratic style of relationship to the cultural heritage of the past. It is caused
N. M. Mamedova
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Prime Time, No. 14 (March, 1980)
The object of Prime Time was to gather information about issues, needs and concerns of women in their middle years. It was co-sponsored by the B.C.
British Columbia Association of Social Workers
core +1 more source
Prime Time, No. 09 (June, 1979)
The object of Prime Time was to gather information about issues, needs and concerns of women in their middle years. It was co-sponsored by the B.C.
British Columbia Association of Social Workers
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

