Results 81 to 90 of about 26,978,530 (253)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Prime Time, No. 03 (April, 1978)
, 1978 The object of Prime Time was to gather information about issues, needs and concerns of women in their middle years. It was co-sponsored by the B.C.
British Columbia Association of Social Workers
core +1 more source
Prime Time, No. 12 (December, 1979)
, 1979 The object of Prime Time was to gather information about issues, needs and concerns of women in their middle years. It was co-sponsored by the B.C.
British Columbia Association of Social Workers
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Prime Time, No. 07 (February, 1979)
, 1979 The object of Prime Time was to gather information about issues, needs and concerns of women in their middle years. It was co-sponsored by the B.C.
British Columbia Association of Social Workers
core +1 more source
Prime Time, No. 10 (August, 1979)
, 1979 The object of Prime Time was to gather information about issues, needs and concerns of women in their middle years. It was co-sponsored by the B.C.
British Columbia Association of Social Workers
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
COVID-19-mandated social restrictions unveil the impact of social time pressure on sleep and body clock. [PDF]
Sci Rep, 2020 Korman M +7 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Prime Time, No. 05 (September, 1978)
, 1978 The object of Prime Time was to gather information about issues, needs and concerns of women in their middle years. It was co-sponsored by the B.C.
British Columbia Association of Social Workers
core +1 more source