Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
"Decentralized Trade, Random Utility and the Evolution of Social Welfare" [PDF]
We study decentralized trade processes in general exchange economies and house allocation problems with and without money. The processes are subject to persistent random shocks stemming from agents' maximization of random utility.
Michihiro Kandori +2 more
core +6 more sources
Data on the existence ratio and social utility of Nash equilibria and of the Perfectly Transparent Equilibrium. [PDF]
Fourny G, Sulser F.
europepmc +1 more source
Nashbots: How Political Scientists have Underestimated Human Rationality, and How to Fix It [PDF]
Political scientists use experiments to test the predictions of game-theoretic models. In a typical experiment, each subject makes choices that determine her own earnings and the earnings of other subjects, with payments corresponding to the utility ...
Enemark, Daniel +2 more
core +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
The global automotive industry’ s rapid transformation has led to electric vehicles (EVs) capturing a significant market share as a sustainable transportation option.
Xiao Zheng +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Demand pre-suppositions in Some Muslim Economists’ Views and Revising them (An Epistemological Analysis of Utility) [PDF]
This paper aims to study some Muslim economists’ views towards pre- suppositions of demand theory in economics, benefiting from the method of analyzing rational behaviors, as well as considering the epistemology of utility.
hasan Agha Nazari
doaj
MANAGEMENT OF SOCIALISATION: A MICROECONOMIC APPROACH [PDF]
The aim of this study is to identify the objective factors of socialization, the driving forces behind individual decisions to achieve a certain level of socialization, the maximization of total utility from socialization, and the mechanisms for ...
Yurii Petrunia +3 more
doaj +1 more source
Beyond Indifferent Players: On the Existence of Prisoners Dilemmas in games with amicable and adversarial preferences [PDF]
Why don’t agents cooperate when they both stand to gain? This question ranks among the most fundamental in the social sciences. Explanations abound. Among the most compelling are various configurations of the prisoner’s dilemma (PD), or public goods ...
Flôres, Renato G. Jr. +1 more
core +1 more source

