Results 121 to 130 of about 1,898,171 (312)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Exploring the role of consistency of social value orientations : temporal stability, reciprocal cooperation, and forgiveness. [PDF]
Many studies of social interaction have incorporated the nature of social value orientations (pro-social vs. pro-self) as an important factor. This paper extends this literature by showing that the effect of the nature of social value orientations is ...
Smeesters, D +2 more
core
OVID-BV: Optimising Value in Decision-Making for Best Value in the UK Social Housing Sector [PDF]
, 2007 The Governments’ promotion and support of Best Value within the Social Housing Sector has been a prime catalyst in the move by Registered Social Landlord’s [RSL’s] away from the traditional culture of acceptance of the lowest bid towards consideration of
Phillips, S.
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Proceedings of the Sixteenth National Symposium on Doctoral Research in Social Work [PDF]
, 2004 The University Archives has determined that this item is of continuing value to OSU's history.The Ohio State University College of Social WorkFront matter: Proceedings title, table of contents ...
Ohio State University. College of Social Work
core
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Social media for social good: Value creation in social media based cause brand communities
, 2015 This thesis presents a case study of value creation in the social media based brand communities of two Australian cause organisations. It improves understanding of how value is created in this increasingly important environment by examining participants'
Sorensen, Anne
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Designing postcapitalist finance in Protocols for Postcapitalist Expression
Finance and SocietyProtocols for Postcapitalist Expression, the Economic Space Agency’s latest experiment in radical economic design, explores the possibility of designing a digitally native economy that is geared towards care, the arts, and the environment, and which not
William Morgan
doaj +1 more source