Results 191 to 200 of about 1,898,171 (312)

The social value of a PASI 90 or PASI 100 response in patients with moderate-to-severe plaque psoriasis in Spain. [PDF]

open access: yesFront Public Health, 2023
Maravilla-Herrera P   +14 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Between the acaderny and queerness : microaggressions in social work education

open access: yes, 2017
Three emerging social work scholars share the results of an authoethnographic study exploring their experiences of microaggressions, related to sexual orientation, in social work academe.
Thompson, Michelle G.   +2 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The impact of inequality on social value orientation: an eye-tracking study. [PDF]

open access: yesFront Psychol
Wang QH   +5 more
europepmc   +1 more source

The role of social value orientation in modulating vaccine uptake in the COVID-19 pandemic: A cross-sectional study. [PDF]

open access: yesHumanit Soc Sci Commun, 2022
Moosa S   +4 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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