Results 71 to 80 of about 142,651 (290)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Emotional reactions of peers influence decisions about fairness in adolescence

open access: yesFrontiers in Human Neuroscience, 2013
During adolescence, peers take on increasing importance, while social skills are still developing. However, how emotions of peers influence social decisions during that age period is insufficiently known.
Eduard T. Klapwijk   +8 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

The Measurement of Social Value Orientation Reconsidered

open access: yes, 2022
Distributional preferences are of central concern for researchers interested in how people make decisions in social contexts. To measure what is sometimes called Social Value Orientation(SVO) respondents are presented with carefully designed sets of joined outcomes and preferences are inferred from their choices.
openaire   +1 more source

Fleur: Social Values Orientation for Robust Norm Emergence

open access: yes, 2022
By regulating agent interactions, norms facilitate coordination in multiagent systems. We investigate challenges and opportunities in the emergence of norms of prosociality, such as vaccination and mask wearing. Little research on norm emergence has incorporated social preferences, which determines how agents behave when others are involved.
Sz-Ting Tzeng   +2 more
openaire   +3 more sources

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Factors affecting behaviour of the participants in the trust game [PDF]

open access: yesTehnika, 2018
In this paper the effect of various factors on the behaviour of participants in the trust game under uncertainty was examined. Numerous experiments have shown that the behaviour of investors and receivers, as well as the results of the investment games ...
Kuzmanović Marija S., Panić Biljana V.
doaj  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

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