Results 61 to 70 of about 31,234 (305)

Including value orientations in choice models to estimate benefits of wildlife management policies (Forthcoming) [PDF]

, 2018
Value orientations towards wildlife affect the way people perceive nature and their connection with animals. In particular, the social psychological literature within the environmental field suggests that there are two main orientations of people towards
Notaro, Sandra, Campbell, Danny, Grilli, Gianluca   +2 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

I really am more important than you: The relationship between the Dark Triad, cognitive ability, and social value orientations in a sample of Japanese adults

Social Sciences and Humanities Open, 2023
This study examined the relationship between the Dark Triad of personality, cognitive ability, and social value orientations. After gender and age were controlled for, dark personality traits and cognitive ability were examined for their predictive ...
Juan Ignacio Lopez, Tadahiro Shimotsukasa, Atsushi Oshio   +2 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The forming of valuable orientations in the process of physical up-bringing [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010
In the article we consider the impact of physical education as an academic subject in the formation of value orientations of students. Value orientations are formed in the face of social experience and reflects in aims, beliefs, ideals, interests ...
Bezverhnya G.V., Mayevskiy N.Y.
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The role of value orientations in evaluating quality of life consequences of a transport pricing policy [PDF]

, 2006
This study examines relationships between value orientations and perceived quality of life-changes when the cost of car use is doubled. An Internet based survey shows that people expect only minor decreases in overall quality of life when costs of car ...
Steg, L., Steg, L.; id_orcid, de Groot, J.I.M.   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Valuable orientations as an indicator of student socialization in the process of professional training

Проблеми сучасної психології, 2017
The conducted studymade it possible to analyze psychological peculiarities of the personality’s socialization of the first-year student, in particular the formation of the value orientations of the personality of the youth in the process of mastering ...
N. P. Panchuk
doaj