Results 131 to 140 of about 1,605,555 (314)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Bringing the Ocean to the Stage: Performing Coastal Values and Marine Management

open access: yesOcean and Society
Recent years have witnessed a seemingly constant call for improved understanding of human–ocean relationships, resulting in a “boom” of marine social science research, sometimes framed through the lens of ocean literacy.
Emma McKinley   +6 more
doaj   +1 more source

Social work in dark places : clash of values in offshore immigration detention

open access: yes, 2016
Social work practice in offshore detention sites is a contested area in Australia. From first-hand experience, this article examines the dilemmas facing a caseworker during the time she was employed by a non-government organisation in Nauru, where ...
Briskman, Linda (R18870), Doe, Jane
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A Heuristic for Integrating Sense of Place Into Ocean Governance

open access: yesOcean and Society
Sense of place (SoP) is a powerful yet underutilised social value with significant potential to improve collaboration and inclusivity in ocean governance. Recent evidence, however, has shown that a range of barriers prevent the routine integration of SoP
Joe Duggan   +3 more
doaj   +1 more source

Social capital and sports clubs

open access: yes, 2014
Book synopsis: This volume provides a collection of critical new perspectives on social capital theory by examining how social values, power relationships, and social identity interact with social capital.
Tacon, Richard
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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