Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Bringing the Ocean to the Stage: Performing Coastal Values and Marine Management
Ocean and SocietyRecent years have witnessed a seemingly constant call for improved understanding of human–ocean relationships, resulting in a “boom” of marine social science research, sometimes framed through the lens of ocean literacy.
Emma McKinley +6 more
doaj +1 more source
Moral and Social Values in Evidence-Informed Deliberative Processes for Health Benefit Package Design Comment on "Evidence-Informed Deliberative Processes for Health Benefit Package Design - Part II: A Practical Guide". [PDF]
Int J Health Policy Manag, 2023 DiStefano MJ.
europepmc +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Humanidades Médicas, 2010 Dentro del proceso de Universalización de la Educación Superior cubana, el fortalecimiento de valores constituye un desafío para las universidades. En este trabajo se aborda la necesidad de perfeccionar el proyecto de trabajo educativo de la brigada ...
Mercedes Bartutis Romero +3 more
doaj
A Heuristic for Integrating Sense of Place Into Ocean Governance
Ocean and SocietySense of place (SoP) is a powerful yet underutilised social value with significant potential to improve collaboration and inclusivity in ocean governance. Recent evidence, however, has shown that a range of barriers prevent the routine integration of SoP
Joe Duggan +3 more
doaj +1 more source
Erratum to "Nurturing positive social values with the Socially Responsible Behaviour through Embodied Thinking (SORBET) Project": Computers and Education Open Volume 2 (2021) 100042. [PDF]
Comput Educ Open, 2022 Lim KYT +4 more
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Nurturing positive social values with the Socially Responsible Behaviour through Embodied Thinking (SORBET) Project. [PDF]
Comput Educ Open, 2021 Lim KYT +4 more
europepmc +1 more source
Values, norms, transactions and organizations [PDF]
This paper may be considered an essay on metaeconomics, since it deals with the meaning of several concepts often left undefined, or very briefly defined in economic theories.
Américo M. S. Carvalho Mendes
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