Results 41 to 50 of about 188,750 (294)

How Valid Are Social Vulnerability Models? [PDF]

Annals of the American Association of Geographers, 2019
Social vulnerability models are becoming increasingly important for hazard mitigation and recovery planning, but it remains unclear how well they explain disaster outcomes.
Rufat, Samuel, Tate, Eric, Emrich, Christopher, Antolini, Federico   +3 more
openaire   +4 more sources

Impact of falling on social participation and social support trajectories in a middle-aged and elderly European sample

SSM: Population Health, 2016
Whereas falls are frequent and traumatic events for the elderly, their long-term consequences in terms of the social lives of older fallers are understudied.
Stéphanie Pin, Dario Spini
doaj  

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Social vulnerability assessment in the health and disease context: Review

Discover Social Science and Health
Background Social vulnerability is a multidimensional concept based on multivariate factors in domains of physical, social, economic, environmental, etc., and the subsets that constitute it.
Arya Mukkil Ashokan, Jegankumar Rajagopal, Prakash Krishnaswamy, Libina Rajendran Sheela, Prashanthi Devi Marimuthu, Dhanabalan Subbiah Pothumani   +5 more
doaj   +1 more source

Measuring social vulnerability to natural hazards at the district level in Botswana

Jàmbá, 2019
Social vulnerability to natural hazards has become a topical issue in the face of climate change. For disaster risk reduction strategies to be effective, prior assessments of social vulnerability have to be undertaken.
Kakanyo F. Dintwa, Gobopamang Letamo, Kennan Navaneetham   +2 more
doaj   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Societal Aspects of Vulnerability to Natural Hazards

Raumforschung und Raumordnung, 2012
To date, social vulnerability research has focused primarily on the individual and household levels, and on social institutions relevant to these two benchmarks.
Swen Zehetmair
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source