Results 61 to 70 of about 12,210,028 (311)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Poverty and Vulnerability - An Interdisciplinary Approach [PDF]

This paper describes the concepts of poverty and vulnerability as well as the interconnections and differences between them using an interdisciplinary approach. While poverty is a static concept, vulnerability has a forward-looking dimension.
Makoka, Donald, Kaplan, Marcus
core  

Theorising local variations on social assistance and its constraints

, 2022
The aim of this chapter is to create a greater theoretical understanding of social welfare, unemployment, and vulnerability among youth and its impacts on a local level.
Uffe Enokson, Rickard Ulmestig, Enokson, Uffe,, Ulmestig, Rickard,   +3 more
core   +1 more source

A theoretical and methodological essay on the concept of vulnerability / Un ensayo teórico y metodológico sobre el concepto de vulnerabilidad

Contexto: Revista de la Facultad de Arquitectura Universidad Autónoma de Nuevo León, 2018
This paper presents a bibliographical review on the concept and methods of identifying vulnerability in urban areas. From systematic bibliographic searches, the main concepts that orbit around vulnerability are defined, as well as their concretion ...
Antonio Palacios García, Pablo Mateos, Carmen Hidalgo Giralt   +2 more
doaj  

Exploitation, Vulnerability, and Social Domination

Philosophy & Public Affairs, 2013
This article attempts to revive a research program by criticizing it. Its object of criticism is the powerful research agenda of analytical Marxism. I shall attempt this revival by criticizing the views of two of the most influential members of that research program, G. A. Cohen and John Roemer.
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Vulnerability: a micro perspective [PDF]

High downside risk to income and livelihoods is part of life in developing countries. Climatic risks, economic fluctuations, and a large number of individual-specific shocks leave these households vulnerable to severe hardship.
Stefan Dercon (QEH)
core  

Spatial and temporal changes of social vulnerability of cities to natural hazards in Zhejiang province, China

Heliyon
Understanding how social dynamics interact with natural hazards is one of the main challenges at global and local scales in the world for studying social vulnerability to natural hazards.
Shanzhong Qi, Shunli Hu, Shufen Cao
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Examining resilience and vulnerability as concepts conditional upon human values: a review [PDF]

Whilst there has been progress in understanding the role that values play in determinations of vulnerability and resilience, I suggest some key points continue to be overlooked.
de Chazal, Jacqueline
core