Results 61 to 70 of about 222,259 (262)

Measurement and impact analysis of social vulnerability to geological disasters in Guizhou Province, China

Scientific Reports
Investigating social vulnerability is a crucial aspect of attaining an in-depth understanding of disasters and disaster risk. This study developed a measurement framework for social vulnerability to geological disasters, obtained a comprehensive social ...
Yan Jia, Shuo Jia, Ruiqiu Pang
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Mapping socio-ecological vulnerability of tropical peatland fires

Environmental Research Letters
Peatlands in Southeast Asia regularly experience fire due to clearance of forests and drainage for agriculture and plantation development. Fire represents a mainstay for rural communities managing tropical landscapes, but these can lead to uncontrolled ...
Janice Ser Huay Lee, Sifeng Wu, Yuti A Fatimah, Stuart W Smith, Nur Estya Bte Rahman, Kwek Yan Chong, Asmadi Saad, Budi Wardhana, Xingli Giam   +8 more
doaj   +1 more source

Societal Aspects of Vulnerability to Natural Hazards

Raumforschung und Raumordnung, 2012
To date, social vulnerability research has focused primarily on the individual and household levels, and on social institutions relevant to these two benchmarks.
Swen Zehetmair
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Lower social vulnerability is associated with a higher prevalence of social media-involved violent crimes in Prince George’s County, Maryland, 2018–2023

Injury Epidemiology
Background Social vulnerability may play a role in social media-involved crime, but few studies have investigated this issue. We investigated associations between social vulnerability and social media-involved violent crimes.
Jemar R. Bather, Diana Silver, Brendan P. Gill, Adrian Harris, Jin Yung Bae, Nina S. Parikh, Melody S. Goodman   +6 more
doaj   +1 more source

Measuring social vulnerability to natural hazards at the district level in Botswana

Jàmbá, 2019
Social vulnerability to natural hazards has become a topical issue in the face of climate change. For disaster risk reduction strategies to be effective, prior assessments of social vulnerability have to be undertaken.
Kakanyo F. Dintwa, Gobopamang Letamo, Kennan Navaneetham   +2 more
doaj   +1 more source