Results 211 to 220 of about 2,045,222 (347)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Creating a Healthy Environment for Children: GIS Tools for Improving the Quality of the Social Welfare Management System. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Źróbek-Różańska A   +2 more
europepmc   +1 more source

The impact of the COVID-19 lockdown on social and economic welfare in Uganda [PDF]

open access: gold
David Musoke   +5 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Epidemiological Profile and Social Welfare Index as Factors Associated with COVID-19 Hospitalization and Severity in Mexico City: A Retrospective Analysis. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Téllez-González MA   +16 more
europepmc   +1 more source

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