Results 21 to 30 of about 2,045,222 (347)

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt   +2 more
wiley   +1 more source

Genetic Causes of Mental Retardation in Bushehr Province

open access: yesJournal of Rehabilitation, 2013
Objective: About 50% of severe to profound intellectual disabilities (ID) are caused by genetic factors. In this study we decided to investigate the genetic causes of ID in 69 Bushehrian families to provide information for genetic counseling, carrier ...
Elaheh Papari   +9 more
doaj  

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

Prevalence of Chronic Diseases Among the Older Adults in Iran: Does Socioeconomic Status Matter?

open access: yesSālmand, 2022
Objectives: Despite the growing population of the elderly in Iran, there is no clear picture of the prevalence of chronic diseases among them. Accordingly, the present study tries to specify the prevalence of the most important chronic diseases and ...
Seyed Hossein Mohaqeqi Kamal   +1 more
doaj  

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan   +5 more
wiley   +1 more source

Comparing Iran\'s Healthcare System Efficiency with OECD Countries Using Data Envelopment Analysis

open access: yesRāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat, 2020
Background: The health sector is one of the most important service sectors and one of the indicators of development and social welfare. The aim of this study is to evaluate the efficiency of Iranchr('39')s health system compared to developed countries ...
Hamed Seddighi   +3 more
doaj  

Parent‐to‐Child Information Disclosure in Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor   +12 more
wiley   +1 more source

Genetic Causes of Mental Retardation in Golestan Province

open access: yesJournal of Rehabilitation, 2010
Objective: About 70 percent of mental retardation can be attributed to genetic causes. Whereas the recognization of genetic causes of mental retardation causes better programming and more precision council for prevention and control of mental retardation,
Hossein Darvish   +9 more
doaj  

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd   +3 more
wiley   +1 more source

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