Results 61 to 70 of about 1,819,903 (248)
Proposal to Strenghern Health Information System [HIS] [PDF]
\ud The HMIS Program described in this document aims at improving and strengthening the current Health Management Information System (HMIS) in Tanzania, known as MTUHA.
Ministry of Health and Social Welfare, (MoHSW)
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Social enterprises in a changing social welfare landscape [PDF]
This paper will explore the genesis of the interest and development of social enterprises in the United Kingdom (U.K.) and how this has been driven by a changing social policy agenda which has provided a framework for the development of social enterprise
Durkin, Chris
core
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Objective: Stuttering is a fairly common speech disorder. However, the etiology is poorly understood and is likely to be heterogeneous. The aim of this research is to investigate phonological encoding complexity on speech fluency in 6-9 year old ...
Sara Ramezani +3 more
doaj
Modernisation and the dynamics of welfare governance
The modernisation of welfare states is high on the agenda of many European nations. The so-called "anglo-saxon" model plays an important, but contradictory, symbolic role, as both a template for reform and as a symbol of the problems of neo-liberal ...
Newman, Janet
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Anthropometric Study of Paraplegic Wheelchair Users in Tehran
Background: Anthropometry is the science of measuring various dimensions of body and use of information obtained in determining the shape and size of workplace and tools used in various fields of industry, education and daily life.
A. Davudian Talab +3 more
doaj
Background Participation in education is a vital component of adolescents’ everyday life and a determinant of health and future opportunities in adult life.
Moa Yngve +4 more
doaj +1 more source

