Results 111 to 120 of about 24,616,697 (377)

Social Development in Africa and the work of the International African Institute [PDF]

, 1945
Hanns Vischer
openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Development and validation of the Global Post Trauma Symptom Scale-Uganda among trauma-affected adults

European Journal of Psychotraumatology
Background: Post-traumatic stress measurement in non-Western contexts often utilizes Western assessment tools.Objective: The purpose of this study was to adapt and validate the Global Post-Trauma Symptom-Item Bank (GPTS-IB) among adult caregivers of ...
Lynn Murphy Michalopoulos, Melissa Meinhart, Erin Walton, David Robertson, Autumn Thompson, Thomas Northrup, Jong Sung Kim, Nikita Aggarwal, Anne Conway   +8 more
doaj   +1 more source

Field Work and Social Research. [PDF]

, 1922
A. L. B., F. Stuart Chapin
openalex   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Social Work handbook [PDF]

, 2000
2000 handbook for the Board of Studies in Social ...
University of Sydney, Social Work
core   +5 more sources

Challenges of mothers of Children with Autism Spectrum Disorder in the Covid- 19 pandemic

دانش و پژوهش در روان‌شناسی کاربردی
This study aimed to investigate and to deeply understand challenges of mothers with autism children in the encountering of Covid-19 epidemic. The current study applies qualitative method. Purposive sampling and information saturating criteria is utilized
Maryam Khakrangin, mansour fathi, Aliye Shahrokhi   +2 more
doaj  

Social Work as a Profession [PDF]

, 1943

openalex   +1 more source