Results 121 to 130 of about 9,587,916 (355)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Community strategies for navigating food insecurity in ward 10, Mudzi District, North Eastern Zimbabwe

open access: yesDiscover Food
Food insecurity remains a pervasive challenge in rural Zimbabwe, with a significant portion of the population struggling to access sufficient and nutritious food.
Tatenda Sukulao   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Scan of Leadership Development Programs [PDF]

open access: yes, 2014
[Original publication date is uncertain.]http://deepblue.lib.umich.edu/bitstream/2027.42/108544/1/Scan_of_Leadership_Development_Programs ...
Skillman Technical Assistance Center, University of Michigan School of Social Work
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Editorial

open access: yesPropuestas Críticas en Trabajo Social, 2021
Propuestas Críticas en Trabajo Social - Critical Proposals in Social Work
doaj  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

LGBTQ + Affirmative CBT: a hierarchical linear model of longitudinal outcomes and mechanisms of change

open access: yesBMC Psychology
Background Sexual and gender diverse adolescents and young adults (SGDAYA) experience mental health disparities, yet few empirical investigations into the long-term impact of affirmative treatments on their well-being exist.
Shelley L. Craig   +9 more
doaj   +1 more source

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