Results 81 to 90 of about 18,064,732 (305)

Care Partner Engagement in Fall Risk Management Programs for Community-Dwelling Older People with Cognitive Impairment: A Systematic Review

open access: yesClinical Interventions in Aging
Xiaoyi Zeng,1 Amelia Card,1,2 Namkee G Choi,1 Yuanjin Zhou1 1School of Social Work, The University of Texas at Austin, Austin, TX, USA; 2Senior Services of Austin, Austin, TX, USACorrespondence: Xiaoyi Zeng, School of Social Work, The University of Texas
Zeng X, Card A, Choi NG, Zhou Y
doaj  

Beyond the Project Cycle: Relational Sustainability in Transdisciplinary Social Innovation in Social Services

open access: yesSocial Sciences
Transdisciplinarity and the co-production of knowledge have become fundamental approaches to addressing complex social problems. However, the sustainability of collaborative partnerships remains underexplored from an empirical perspective.
Luna del Alba Anillo Pérez   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Islamic Faith-Based Organizations and Poverty Reduction in Bangladesh: A Social Work Perception

open access: yesSocial Work and Society, 2020
The development studies have traditionally neglected the role of religious faith and its role in the lives of the poor throughout the developing world.
Isahaque Ali   +4 more
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Everyday ethics in professional life: social work as ethics work

open access: yes, 2016
This article outlines and develops the concept of ‘ethics work’ in social work practice. It takes as its starting point a situated account of ethics as embedded in everyday practice: ‘everyday ethics’.
Sarah Banks
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy