Results 81 to 90 of about 24,616,697 (377)
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Addiction Science & Clinical PracticeBackground In the U.S. there are significant racial and gender disparities in the uptake of pre-exposure prophylaxis (PrEP). Black Americans represented 14% of PrEP users in 2022, but accounted for 42% of new HIV diagnoses in 2021 and in the South, Black
Dawn Goddard-Eckrich +12 more
doaj +1 more source
Social media: a guide for researchers [PDF]
, 2011 This guide has been produced by the International Centre for Guidance Studies, and aims to provide the information needed to make an informed decision about using social media and select from the vast range of tools that are available.
Cann, Alan +2 more
core +1 more source
Validation of the Greek translation of the multicultural quality of life index (MQLI-gr)
Health and Quality of Life Outcomes, 2020 Background The aim of the current study was to examine the internal structure and convergent and discriminant validity of the Multicultural Quality of Life Index (MQLI) in a Greek sample of community-dwelling adults in a major Greek city.
Effrosyni D. Kokaliari, Ann W. Roy
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
The living environments of community-dwelling older people who become frail: another look at the living standards of older New Zealanders survey. [PDF]
, 2006 Efforts to support older people who live in the community and who become frail will be enhanced by a better appreciation of the shared characteristics of this group.
Barrett, Patrick +3 more
core +1 more source
Molecular Oncology, Volume 19, Issue 7, Page 2133-2143, July 2025.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Should physical activity be on the healthy ageing agenda? [PDF]
, 2008 Physical activity makes a notable contribution to one’s independence, ability to perform everyday tasks and quality of life in the later years, but engagement in this health-related behaviour decreases with age.
Grant, Bevan C.
core +1 more source
Everyday ethics in professional life: social work as ethics work
, 2016 This article outlines and develops the concept of ‘ethics work’ in social work practice. It takes as its starting point a situated account of ethics as embedded in everyday practice: ‘everyday ethics’.
Sarah Banks
semanticscholar +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, Volume 19, Issue 7, Page 1968-1978, July 2025.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source