Results 81 to 90 of about 1,804,339 (267)

Challenges of mothers of Children with Autism Spectrum Disorder in the Covid- 19 pandemic

open access: yesدانش و پژوهش در روان‌شناسی کاربردی
This study aimed to investigate and to deeply understand challenges of mothers with autism children in the encountering of Covid-19 epidemic. The current study applies qualitative method. Purposive sampling and information saturating criteria is utilized
Maryam Khakrangin   +2 more
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Health literacy and coronavirus guideline adherence among families in Mexico

open access: yesClinical Epidemiology and Global Health
Problem considered: The COVID-19 pandemic severely impacted Mexico, where misinformation and limited health literacy (HL) may have influenced public adherence to preventive guidelines. Prior studies have suggested that HL plays a critical role in shaping
Steven Hoffman   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Development and validation of the Global Post Trauma Symptom Scale-Uganda among trauma-affected adults

open access: yesEuropean Journal of Psychotraumatology
Background: Post-traumatic stress measurement in non-Western contexts often utilizes Western assessment tools.Objective: The purpose of this study was to adapt and validate the Global Post-Trauma Symptom-Item Bank (GPTS-IB) among adult caregivers of ...
Lynn Murphy Michalopoulos   +8 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Editorial

open access: yesPropuestas Críticas en Trabajo Social, 2021
Propuestas Críticas en Trabajo Social - Critical Proposals in Social Work
doaj  

Barriers and facilitators of preventive healthcare access among immigrants in rural America: a scoping review

open access: yesInternational Journal for Equity in Health
Preventive healthcare services are essential for improving health outcomes and reducing disparities; however, immigrant populations in rural America face significant barriers to accessing such care.
Yingying Zeng   +3 more
doaj   +1 more source

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