Results 81 to 90 of about 24,718,869 (254)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Xiaoyi Zeng,1 Amelia Card,1,2 Namkee G Choi,1 Yuanjin Zhou1 1School of Social Work, The University of Texas at Austin, Austin, TX, USA; 2Senior Services of Austin, Austin, TX, USACorrespondence: Xiaoyi Zeng, School of Social Work, The University of Texas
Zeng X, Card A, Choi NG, Zhou Y
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
2009 Agenda: The 21st National Symposium on Doctoral Research in Social Work
The University Archives has determined that this item is of continuing value to OSU's history.The Ohio State University College of Social ...
Ohio State University. College of Social Work
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Background Gender-based violence (GBV) is a serious public health issue and violation of human rights that disproportionately impacts refugee women. This qualitative study explores GBV among urban refugee women in Nairobi, Kenya, using the migration ...
Lena Moraa Obara +7 more
doaj +1 more source
Foster Care on the Market: Swedish Independent Foster Care Agencies in an International Context
In recent decades, a new type of organisation—independent foster care agencies (IFAs)—has emerged in Sweden and other countries. These organisations operate outside the public sector, marking a significant shift in how foster care is provided.
Evelina Fridell Lif +4 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
2008 Photo Gallery: 20th National Symposium on Doctoral Research in Social Work
The University Archives has determined that this item is of continuing value to OSU's history.The Ohio State University College of Social ...
Ohio State University. College of Social Work
core +1 more source

