Results 51 to 60 of about 5,330,925 (307)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dilemmas in doing insider research in professional education [PDF]

, 2012
This article explores the dilemmas I encountered when researching social work education in England as an insider researcher who was simultaneously employed as an educator in the host institution.
Adler PA, Christians CG, Clarke CL, Coghlan D, Fook J, Gould N, Honey P, Humphrey C, Lee RM, Payne M, Potts A, Punch M, Rabinow P, Ryan M, Shaw I, Smyth A, Titchen A, Vitali S   +17 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The Development of a Train-the-Trainer Approach in Reciprocal Reading Instruction in England’s Primary Schools

Education Sciences
There is good evidence that targeted reciprocal reading instruction for struggling readers can lead to attainment gains in reading for children aged 9–12 years in England using the FFT Reciprocal Reading instruction programme when training is delivered ...
Maria Cockerill, Joanne O’Keeffe, Allen Thurston, Canan Ozkaya, Joanne Holland, Andy Taylor   +5 more
doaj   +1 more source

Social work education and carcerality [PDF]

, 2014
This doctoral study examined the experiences of social work practitioners who became social work academics. Interviews with social work academics from five English universities explored career pathways, transition experiences and engagement with ...
Simpson, Diane
core  

'Baptism of Fire': The First Year in the Life of a Newly Qualified Social Worker. [PDF]

, 2009
This paper describes research commissioned by Skills for Care South West to identify and track the learning and development needs of newly qualified social workers through their first year of employment.
Bates, Natalie, Brown, Keith, Immins, Tikki, Keen, Steven, Parker, Jonathan, Rutter, Lynne, Zsigo, Sharon   +6 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Evaluating the Effects of the Crescendo Programme on Music and Self-Regulation with 5–6-Year-Old Pupils: A Quasi-Experimental Study

Education Sciences
Crescendo is a music-based social and emotional learning (SEL) programme designed for primary/elementary school children living in disadvantaged communities.
Liam O’Hare, Conneth Poland, Leeanne O’Hara, Aideen Gildea, Junyi Wang, Sarah Miller, Laura Dunne   +6 more
doaj   +1 more source

A paradigmatic map of professional education research [PDF]

, 2011
This article maps out research in professional education with reference to a threefold typology of paradigms i.e. the positivist, interpretivist and critical paradigms. The rationale for such an endeavour is fourfold.
Humphrey, Caroline
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source