Results 61 to 70 of about 236,324 (311)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Social Work/Maatskaplike Werk, 2011 Most movie enthusiasts were intrigued by the film Slumdog Millionaire. This story reflects, amongst other issues, the survival strategies of kids living on the streets in towns in India and the happy ending for one of them.
Juliet MacDonald, Susan Terblanche
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Other title: Counselor, Social Worker, and Marriage and Family Therapist Board news
, 2014 2 issues yearly; Began with Fall 2014, Issue 2.; Harvested from the web on 3/13 ...
Ohio. Counselor, Social Worker, and Marriage and Family Therapist Board.
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
TRAUMA IS THE “STEALING OF MY SENSE OF BEING ME”: A PERSON-CENTRED PERSPECTIVE ON TRAUMA
Social Work/Maatskaplike Werk, 2012 Exposure to trauma has always been part of human existence (Marsella, Friedman & Spain, 1996). Extreme stress has been depicted by authors throughout the ages.
Barbara Wade, Rinie Schenck
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
POVERTY IN A RURAL AREA: THE ROLE OF THE SOCIAL WORKER
Social Work/Maatskaplike Werk, 2008 There are many ways of looking at poverty. When poverty is measured in absolute terms, itrefers to the financial means necessary for people to survive from day to day.
C Strydom, ME Tlhojane
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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