Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The Impact of Late-Career Health and Employment Shocks on Social Security and Other Wealth [PDF]
, 2007 About one-quarter of workers age 51 to 55 in 1992 developed health-related work limitations and about one-fifth were laid off from their jobs before age 62.
Dan Murphy +2 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Insights from a retrospective study: an understanding of pediatric colorectal carcinoma
Egyptian Pediatric Association GazettePediatric colorectal cancer, comprising just 1% of childhood cancers, has surged among young individuals, underscoring its significant health impact. Diagnostic challenges arise from atypical presentation and nonspecific symptoms in 90% of cases, leading
Sofia Brenes Guzmán +7 more
doaj +1 more source
¿Quo Vadis? Reclutamiento y Contratacion de Trabajadores Migrantes y su Acceso a la Seguridad Social: dinamicas de los sistemas de trabajo temporal migratorio en Norte y Centroamerica [PDF]
, 2013 Different regions and countries of the world face a serious need to design and make use of necessary policies and resources to better manage worker migration, thus ensuring the welfare and human rights of these people who, in the end, are of benefit to ...
Alejandra Costanza, Gisele Lisa Bonnici
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Social Protection of Rural Workers in the Construction Industry in Urban China [PDF]
The construction industry is important for Chinese rural to urban migrants. Over 90% of urban construction workers are rural migrants, and over a third of all rural migrants work in construction.
Bingqin Li, Huamin Peng
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
16PF Personality Profiles for Social Workers: Form A/Form S Comparisons [PDF]
, 1992 The goal of this report was to identify the distinguishing features of 16PF personality profiles for social workers that have been collected with Experimental Form S (prototype of Fifth Edition 16PF Questionnaire).
Guastello, Stephen J.
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source