Results 121 to 130 of about 2,765,395 (317)

CPD curriculum guide for social workers who are working with people on the autism spectrum [PDF]

open access: yes, 2015
Tizard Centre, Centre for Child Protection (2015) “A report on autism for social workers” Commissioned by The College of Social Work (written and published by the Dept.
Reeves, Jane
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Youth and Experience of Traffic Accidents (Grounded Theory)

open access: yesHealth in Emergencies & Disasters Quarterly, 2017
Background: Traffic accidents are among major causes of death all over the world. In Iran, it has become a social problem, with lots of people involved in; and the youth include the most victims of traffic accidents.
Sayyed-Muhammad-Hossein Javadi   +4 more
doaj  

Taper BSV-profesjonene posisjoner i helse- og velferdstjenestene?

open access: yesTidsskrift for velferdsforskning
I artikkelen stiller vi spørsmålet om barnevernspedagoger, sosionomer og vernepleiere (BSV-profesjonene) taper posisjoner i helse- og velferdstjenestene.
Øystein Henriksen   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Raising the Social Security Payroll Tax Cap: How Many Workers Would Pay More? [PDF]

open access: yes, 2013
On January 1, the maximum amount of annual earnings subject to the Social Security tax -- a.k.a. the payroll tax cap -- increased to $113,700. Every year, this cap is adjusted to keep up with inflation.
Janelle Jones, John Schmitt, Nicole Woo
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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