Results 231 to 240 of about 534,829 (305)

A Life of Commitment [PDF]

, 1970
Stanton, Joseph R.
core   +2 more sources

Sirt3 Genetically Engineered Apoptotic Bodies Alleviate Skeletal Aging by Limiting Aggravated NLRP3 Inflammasome Activation of Senescent Macrophages

Advanced Science, EarlyView.
The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu, Shifeng Ling, Jiayi Mao, Hongyi Wang, Bo Wang, Zhenjia Che, Wenguo Cui, Ming Cai   +7 more
wiley   +1 more source

Capacity, motivation, and opportunity model-derived taxonomy of pharmacist-led interventions applicable to people self-managing cancer medication. [PDF]

Front Public Health
Ribeiro J, Morillo-Verdugo R, Alves da Costa F.   +2 more
europepmc   +1 more source

It is all about value now: The data you need to collect and how to do it [PDF]

, 2018
Bozic, Kevin J, Goldfarb, Charles A, Lieberman, Jay R, Mallon, William J   +3 more
core   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Trauma and Orthopaedic Surgery: The Spanish Model. [PDF]

J Bone Joint Surg Am
Rojas-Sayol R, Monfort-Mira M, Martínez de Albornoz P, Ortega-Briones A, Bernaus M.   +4 more
europepmc   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

Advanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan, Peng Li, Yue Wang, Xin Qi, Wanyu Wang, Yongzhong Cheng, Huabin Zhang, Xin Hu, Xiang Gao   +8 more
wiley   +1 more source

Development of a medical screening process for patients with acute psychiatric symptoms presenting to the emergency department: protocol for a modified international Delphi study. [PDF]

BMJ Open
Ünlü L, Carpenter CR, Sterzer P, Griese JA, Chrobok L, Minotti B, Christ M, Nordstrom K, Skinner C, Lunardi C, Alsma J, Bingisser R, Wilson MP, Nickel CH.   +13 more
europepmc   +1 more source

The Suspension of Alcoholic Chlorhexidine in Italy: The Risk of a Therapeutic Gap Between Regulation and Clinical Practice. [PDF]

Hosp Pharm
Castellana E, Chiappetta MR.
europepmc   +1 more source

The Purchase of Medical Care Through Fixed Periodic Payment [PDF]

Pierce Williams
core