Results 61 to 70 of about 534,829 (305)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mundo hospital: enfermedad y formas de vida en las sociedades actuales / Hospital World: Disease and ways of life in today's societies

Kamchatka: Revista de Análisis Cultural, 2017
Monográfico ...
Miguel Ángel Martínez García
doaj   +3 more sources

Global neurosurgery amongst the EANS community: Where are we at?

Brain and Spine, 2022
Nicolò Marchesini, Marcel Ivanov, Jesus Lafuente, Francesco Sala, Nikos Foroglou, Massimiliano Visocchi, Fatos Olldashi, Pablo Gonzalez-Lopez, Jamil Rzaev, Magnus Tisell, Vincenzo Paternò, Kresimir Rotim, Jake Timothy, Lukas Rasulic, Andreas K. Demetriades   +14 more
doaj   +1 more source

Interpersonal and systemic factors in initiating, developing and maintaining collaborations between European neurosurgical departments and institutions in low-resources settings: A qualitative study

Brain and Spine
Introduction: Neurosurgical care in low- and middle-income countries faces persistent challenges, including insufficient infrastructure, lack of trained surgeons, and limited access to sustainable training programs.
Nicolò Marchesini, Vicki M. Butenschoen, Andreas K. Demetriades, Said Idrissa Ahmada, Fazlul Hoque, Thomas Kapapa, Patrick D. Kamalo, Pablo González-López, Rupavathana Mahesperan, Ondra Petr, Wilco Peul, Nicephorus Boniface Rutabasibwa, Ellianne J. dos Santos Rubio, Abenezer Tirsit Aklilu, Jake Timothy, Enoch O. Uche, Magnus Tisell   +16 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Working in low- and middle-income countries: Learning from each other

Brain and Spine, 2022
Jake Timothy, Marcel Ivanov, Magnus Tisell, Nicolò Marchesini, Jesus Lafuente, Nikos Foroglou, Massimiliano Visocchi, Fatos Olldashi, Pablo Gonzalez-Lopez, Jamil Rzaev, Peter Whitfield, Wilco C. Peul, Lukas Rasulic, Andreas K. Demetriades   +13 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Perceived effectiveness and recommendations from a childbirth quality assurance and improvement programme in India’s private sector: a qualitative evaluation using the RE-AIM framework

BMJ Public Health
Introduction Previous studies have revealed inconsistent quality of care in India’s private sector, where nearly one in three facility births take place.
Katherine Semrau, Meghna Desai, Lauren Spigel, Somesh Kumar, Megan Marx Delaney, Lauren Bobanski, Suranjeen Pallipamula, Natalie Henrich, Tapas Sadasivan Nair, Hema Divakar, Rajat Chabba, Shweta Jindal, Gulnoza Usmanova, Sukanya Dutta, Aarushi Gupta, Sucheta Kinjawadekar, Priti Kumar, Priyanka Kumari, Prerna Mukharya, Hrishikesh Pai, Ameya Purandare, Pompy Sridhar   +21 more
doaj   +1 more source

History and development of ophthalmology in Taiwan

Journal of the Formosan Medical Association, 2016
Western medicine was first introduced to Taiwan by medical missionaries in the mid-19th century. Modernization of medicine was systematically transplanted to Taiwan in the Japanese colonial period, and ophthalmology was established third among hospital ...
Yu-Chih Hou, Gale A. Oren, Muh-Shy Chen, Fung-Rong Hu   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source