Results 51 to 60 of about 3,967,313 (340)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Lessons from Corporate Influence in the Opioid Epidemic: Toward a Norm of Separation

Journal of Bioethical Inquiry, 2020
There is overwhelming evidence that the opioid crisis—which has cost hundreds of thousands of lives and trillions of dollars (and counting)—has been created or exacerbated by webs of influence woven by several pharmaceutical companies. These webs involve
J. Marks
semanticscholar   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Health literacy levels and self-rated health in the state of Delaware: a cross-sectional study

Discover Social Science and Health
Background Better health literacy has been found to be associated with better health outcomes across varied populations. This study aimed to (1) examine the health literacy levels of individuals with respect to the extent to which they acquire ...
Raymond A. Tutu, Edmund Essah Ameyaw, John Kwagyan, Doris Ottie-Boakye   +3 more
doaj   +1 more source

The Santa Clara Dental Pharmaceutical Body, the first Villa Clara Scientific Society

Acta Médica del Centro, 2020
Introduction: the Medical-Dental-Pharmaceutical Corps, founded on December 11, 1892 in Santa Clara, was one of the oldest and most enduring scientific societies in Cuba.
José Ramón Ruiz Hernández, Lilian Esther Ruiz González   +1 more
doaj  

Patient’s medicinal knowledge in Saudi Arabia:

Saudi Pharmaceutical Journal, 2016
Patient education is one of the main factors of patient therapeutic plan and without it, the patient may not benefit from his/her medications. Several studies showed the effectiveness of educating patients about their disease(s) and their medication(s ...
Thamir M. Alshammari
doaj   +1 more source

Mobility and Policy Responses During the COVID-19 Pandemic in 2020

International Journal of Public Health, 2022
Objective: This paper quantitatively explores determinants of governments’ non-pharmaceutical policy responses to the COVID-19 pandemic. Our focus is on the extent to which geographic mobility affected the stringency of governmental policy responses ...
Gabriel Cepaluni, Michael T. Dorsch, Michael T. Dorsch, Daniel Kovarek   +3 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Clinico-epidemiological evaluation of pharmaceutical/non-pharmaceutical poisoning in a referral poisoning emergency in the Central part of Iran

Scientific Reports
The pattern of poisoning varies in different societies. In this study, we investigated the clinical-epidemiological features and outcomes of poisoned patients based on the substances involved, whether pharmaceutical or non- pharmaceutical toxins.
Nastaran Eizadi-Mood, Hamed Sanjari, Awat Feizi, Razieh Yazdi, Amin Dorostkar, Razieh Mahvari, Parisa Mirmoghtadaee, Rokhsareh Meamar   +7 more
doaj   +1 more source