Results 61 to 70 of about 3,967,313 (340)

Antiviral Efficacy of Molnupiravir for COVID-19 Treatment

open access: yesViruses, 2022
The ongoing global pandemic of COVID-19 poses unprecedented public health risks for governments and societies around the world, which have been exacerbated by the emergence of SARS-CoV-2 variants. Pharmaceutical interventions with high antiviral efficacy
Yuan Bai, Mingwang Shen, Lei Zhang
doaj   +1 more source

Child and Adolescent Mental Health Around The World: Challenges for Progress [PDF]

open access: yes, 2005
Child and adolescent mental health is an essential component of overall health and its importance is gaining increased recognition. Current events have heightened an interest in the mental health of youth. Unfortunately, too often this is due to concerns
Belfer, Myron L
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Report on Proceedings of the Sixth Annual Meeting of the European CME Forum, London, UK, 14–15 November 2013

open access: yesJournal of European CME, 2014
Delegates from around the world attended the sixth annual meeting of the European CME Forum in London between 14 and 15 November 2013. The participants discussed best practices in continuing medical education and continuing professional development (CME ...
Ron Murray
doaj   +1 more source

Optimizing Effectiveness in Electronic Prescriptions for Pediatric Outpatients: A Call for Responsive Action

open access: yesPharmacy, 2014
A pediatric compounded non-sterile products repository (pCNP) to optimize the effectiveness and safety of “off-label” use of compounded pharmacotherapy through complete transmission of electronic prescriptions across the continuum of care is described ...
Richard H. Parrish II   +5 more
doaj   +1 more source

Epidemics Forecast From SIR-Modeling, Verification and Calculated Effects of Lockdown and Lifting of Interventions

open access: yesFrontiers in Physics, 2021
Due to the current COVID-19 epidemic plague hitting the worldwide population it is of utmost medical, economical and societal interest to gain reliable predictions on the temporal evolution of the spreading of the infectious diseases in human populations.
R. Schlickeiser   +2 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein   +13 more
wiley   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy