Results 91 to 100 of about 2,210,793 (307)

Needs and challenges among physicians and researchers in thrombosis and hemostasis: Results from an international study

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2019
Background Specialty societies, such as the International Society on Thrombosis and Haemostasis (ISTH), are a key source of support for clinical and scientific communities, through the provision of educational activities, tools, and resources to support ...
Suzanne Murray   +8 more
doaj   +1 more source

Down to Earth: Planetary Health and Biophilosophy in the Symbiocene Epoch

open access: yesChallenges, 2017
Advances in science have illuminated the role of the “ecological theatre”—the total living environment—in human health. In a rapidly changing epoch known as the anthropocene, microbiome science is identifying functional connections between all life, both
Susan L. Prescott, Alan C. Logan
doaj   +1 more source

Social Preferences in Small‐Scale Societies [PDF]

open access: yes, 2005
This volume reports on a cross‐cultural investigation of social preferences in 15 small‐scale, non‐Western societies. Participants from all 15 groups played the ultimatum game with members of their own culture; subjects from a subset also played dictator
Field, Alexander J.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The Added Value of Black Engineering Students’ Participation in Identity-based Organizations: A Systematic Literature Review

open access: yesStudies in Engineering Education
Background: Black students are an integral part of engineering education. However, despite millions of investments in broadening participation in engineering, they remain underrepresented in engineering.
Julia Machele Brisbane   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Astrofood, Priorities and Pandemics: Reflections of an Ultra-Processed Breakfast Program and Contemporary Dysbiotic Drift

open access: yesChallenges, 2017
Recognizing the importance of nutrition as part of the grand challenges faced by humanity—the current epidemic of non-communicable diseases (NCDs), sustainability and maintenance of Planetary Health—the United Nations (UN) has declared 2016–2025 the ...
Alan C. Logan, Susan L. Prescott
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Support Science by Publishing in Scientific Society Journals

open access: yesmBio, 2017
Scientific societies provide numerous services to the scientific enterprise, including convening meetings, publishing journals, developing scientific programs, advocating for science, promoting education, providing cohesion and direction for the ...
Patrick D. Schloss   +2 more
doaj   +1 more source

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