Results 71 to 80 of about 403,592 (267)

Enfermagem e Sindicalismo em Goiás: análise do período 1982-2004 Enfermería y Sindicalismo en Goiás: análisis del período 1982-2004 Nursing and Unionism in Goiás: analysis of the period from 1982 to 2004

open access: yesRevista Brasileira de Enfermagem, 2007
Estudos sobre Sindicalismo e Enfermagem são bastante escassos no Brasil. Em Goiás, só encontramos uma monografia acerca do tema, o que nos levou a examinar a questão. Este trabalho tem como objetivo analisar o sindicalismo na área de enfermagem em Goiás,
Viviane Lemes da Silva Carvalho   +1 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Book review: eds. Romulo Pinheiro, Maria Laura Frigotto, Mitchell Young (2022), Towards resilient organizations and societies: a cross-sectoral and multi-disciplinary perspective, Palgrave Macmillian, (eBook) [PDF]

open access: yesApplied Research in Administrative Sciences
The book titled “Towards Resilient Organizations and Societies: A Cross-sectoral and Multi-disciplinary Perspective” is part of the series “Public Sector Organizations “, a series that covers issues such as: the methodology for studing public sector ...
PROFIROIU Alina-Georgiana
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

ШЕВЧЕНКІАНА КИЇВСЬКОЇ ГРОМАДИ ЯК СУСПІЛЬНО-НАУКОВИЙ ПРОСТІР

open access: yesПростір в історичних дослідженнях, 2023
У статті розглянуто аспекти, пов’язані з діяльністю Київської Громади як основного осередку українофільського руху другої половини ХІХ – початку ХХ ст. Зокрема, акцентується на науковому вивченні її представниками життя та творчості Т. Г.
Катерина Нагайко
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Intercultural dialogue n post modern societies and its political implication - Georgian case [PDF]

open access: yesAnte Portas
This article deals with the topic of intercultural dialogue in postmodern societies and discusses its political implications particularly focuses on the case of Georgia, and analyzes the extreme importance of intercultural dialogue in today’s diverse ...
Eka Beraia, Mariam Dalakishvil
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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