Results 71 to 80 of about 2,210,793 (307)

The Evolution of Primate Societies - Chapter 3 [PDF]

open access: yes, 2012
Compared with other primates, New World monkeys display relatively limited ecological variability. New World monkey anatomy and social systems, however, are extremely diverse.
Di Fiore, Anthony   +2 more
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Pure vs. Mutual Sick Insurance Societies. Evidence from Swedish Historical Data [PDF]

open access: yes
Using data from voluntary Swedish sick insurance societies 1902-1910, this paper analyzes the coexistence of pure and mutual insurance societies where pure societies are characterized by charging ex ante premiums only while mutuals in addition charge ex ...
Nekby, Lena
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

“Tiettyjen maakuntalaulujen laulaminen elähdyttää enemmän kuin toisten maakuntalaulujen.” Jäsenyyden vetotekijät 2010-luvun Turun yliopiston osakunnissa

open access: yesJ@rgonia, 2022
Artikkelissani tutkin Turun yliopiston 2010-luvun osakuntayhteisöjen luonnetta. Kysyn, miten osakunnan jäsenet kokevat osakunnan merkityksen ja siihen kuulumisen?
Säisä, Mari
doaj  

Entrevista com Renato Ortiz

open access: yesRevista Internacional de Folkcomunicação, 2017
Nowadays, the politically correct participation of all faces the balkanization or fragmentation of societies into small groups of desires that defend their own rights, as well as increasing hostility against immigration and omulticulturalism.
Sonia Regina S. da Cunha
doaj   +1 more source

Resource dependent branching processes and the envelope of societies

open access: yes, 2015
Since its early beginnings, mankind has put to test many different society forms, and this fact raises a complex of interesting questions. The objective of this paper is to present a general population model which takes essential features of any society ...
Bruss, F. Thomas, Duerinckx, Mitia
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Communicative Societies

open access: yesПроблеми на постмодерността, 2012
Communication and globalization are strongly linked processes, and in this article is shown just that, as well as the "noises" which prevent meaningful communication of the societies.
Evgeni Vasilev
doaj  

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