Results 61 to 70 of about 403,592 (267)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Em contato com a violência: os profissionais de saúde e seus pacientes vítimas de maus tratos En contacto con la violencia: los profesionales de la salud y sus pacientes víctimas de malos tratos In contact with the violence: the health care professionals and their patients victims of abuse

open access: yesRevista Latino-Americana de Enfermagem, 2000
Utilizando-se de uma abordagem qualitativa, esse artigo delineia a percepção de profissionais de saúde, sobretudo pediatras, acerca da violência e sua responsabilidade em denunciar os casos que vivenciaram.
Marlene Braz, Maria Helena C.A. Cardoso
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Civil Society, Information Society, Islamic Society

open access: yes, 1998
The concept of civil society, as a intellectual framework for describing development in modern European and other industrial societies, has been the dominant discourse in philosophical and sociological thought from the 19th century onwards (Keane 1988a and 1988b).
openaire   +1 more source

Proceedings of Learned Societies. Geological Society [PDF]

open access: yesAnnals and Magazine of Natural History
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources

Communicative Societies

open access: yesПроблеми на постмодерността, 2012
Communication and globalization are strongly linked processes, and in this article is shown just that, as well as the "noises" which prevent meaningful communication of the societies.
Evgeni Vasilev
doaj  

Primates et Sociétés : La sortie de l’état de nature

open access: yesRevue de Primatologie, 2012
Rousseau’s three centenary is a good opportunity to introduce his fundamental ideas and to apply them to new domains, such as primatology. The concept of the state of nature, developed in the first part of the second Discourse, and the dichotomy between ...
Thomas Robert   +1 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Rescatando retazos de la memoria docente: la primera asociación de maestros de Mendoza, 1904-1914. Recovering fragments of teaching memory: first association of teachers in Mendoza, 1904-1914.

open access: yesCabás, 2014
(ES) El propósito de esta contribución consiste en examinar los orígenes de las primeras organiza-ciones de maestras/os de Mendoza -Argentina, surgidas a fines del siglo XIX y principios del XX.
Patricia I. Dussel
doaj  

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