Results 121 to 130 of about 1,999,921 (311)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Double-interval societies [PDF]

open access: yesarXiv, 2013
Consider a society of voters, each of whom specify an approval set over a linear political spectrum. We examine double-interval societies, in which each person's approval set is represented by two disjoint closed intervals, and study this situation where the approval sets are pairwise-intersecting: every pair of voters has a point in the intersection ...
arxiv  

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

open access: yesMolecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda   +3 more
wiley   +1 more source

Intercultural relations, bodies speech and semiopraxis [PDF]

open access: yesAlteridad : Revista de Educación, 2010
La línea de investigación que proponemos pone en diálogo el trabajo conjunto de redes de investigación latinoamericana, fundamentalmente,las que tienen vinculación con movimientos y actores sociales, no necesariamente académicos, como por ejemplo el ...
José Luis Grosso
doaj  

Society Functions Best with an Intermediate Level of Creativity [PDF]

open access: yesProceedings of the Annual Meeting of the Cognitive Science Society (pp. 1578-1583). August 1-4, Sapporo Japan. Houston TX: Cognitive Science Society (2012), 2013
In a society, a proportion of the individuals can benefit from creativity without being creative themselves by copying the creators. This paper uses an agent-based model of cultural evolution to investigate how society is affected by different levels of individual creativity.
arxiv  

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

Societal, Economic, Ethical and Legal Challenges of the Digital Revolution: From Big Data to Deep Learning, Artificial Intelligence, and Manipulative Technologies [PDF]

open access: yesarXiv, 2015
In the wake of the on-going digital revolution, we will see a dramatic transformation of our economy and most of our societal institutions. While the benefits of this transformation can be massive, there are also tremendous risks to our society. After the automation of many production processes and the creation of self-driving vehicles, the automation ...
arxiv  

Culture and Society [PDF]

open access: yesSurvival, 2019
The Psychology of Pandemics: Preparing for the Next Global Outbreak of Infectious DiseaseSteven Taylor. Newcastle upon Tyne: Cambridge Scholars Publishing, 2019. £19.99. 178 pp.
openaire   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

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