Results 121 to 130 of about 1,999,921 (311)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
Double-interval societies [PDF]
Consider a society of voters, each of whom specify an approval set over a linear political spectrum. We examine double-interval societies, in which each person's approval set is represented by two disjoint closed intervals, and study this situation where the approval sets are pairwise-intersecting: every pair of voters has a point in the intersection ...
arxiv
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda+3 more
wiley +1 more source
Intercultural relations, bodies speech and semiopraxis [PDF]
La línea de investigación que proponemos pone en diálogo el trabajo conjunto de redes de investigación latinoamericana, fundamentalmente,las que tienen vinculación con movimientos y actores sociales, no necesariamente académicos, como por ejemplo el ...
José Luis Grosso
doaj
Society Functions Best with an Intermediate Level of Creativity [PDF]
In a society, a proportion of the individuals can benefit from creativity without being creative themselves by copying the creators. This paper uses an agent-based model of cultural evolution to investigate how society is affected by different levels of individual creativity.
arxiv
The roles and applications of extracellular vesicles in cancer
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
Societal, Economic, Ethical and Legal Challenges of the Digital Revolution: From Big Data to Deep Learning, Artificial Intelligence, and Manipulative Technologies [PDF]
In the wake of the on-going digital revolution, we will see a dramatic transformation of our economy and most of our societal institutions. While the benefits of this transformation can be massive, there are also tremendous risks to our society. After the automation of many production processes and the creation of self-driving vehicles, the automation ...
arxiv
The Psychology of Pandemics: Preparing for the Next Global Outbreak of Infectious DiseaseSteven Taylor. Newcastle upon Tyne: Cambridge Scholars Publishing, 2019. £19.99. 178 pp.
openaire +3 more sources
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka+10 more
wiley +1 more source