Results 191 to 200 of about 2,627 (289)

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Impacts of Climate Change on the Spatial Distribution and Habitat Suitability of <i>Nitraria tangutorum</i>. [PDF]

Plants (Basel)
Li L, Jia Z, He L, Han D, Yang Q, Li J, Zhou P.   +6 more
europepmc   +1 more source

High atmospheric pressure rescues plant growth under humidity stress: A model for climate‐resilient deep underground agriculture

Deep Underground Science and Engineering, EarlyView.
High atmospheric pressure (120 kPa) in deep underground counteracts humidity‐induced physiological stress in plants, stabilizing water balance and enhancing antioxidative defenses. This synergy boosts biomass despite elevated humidity, demonstrating sustainable deep underground agriculture potential under climate uncertainty.
Yuxin He, Linglu Xu, Xiao Tan, Wenhua Zhuang, Naiwen Li, Chao Liu, Bo Tan   +6 more
wiley   +1 more source

Spatial analysis and mapping of intensity and types of agricultural salt-affected soils around Abaya and Chamo Lakes, South Ethiopia Rift Valley. [PDF]

Heliyon
Walche A, Haile W, Kiflu A, Tsegaye D.
europepmc   +1 more source

Enhanced Electron‐Capturing by Single‐Atomic Iron on Pyridinic N‐Deficient Carbon Drives Self‐Oxidative Degradation of Pollutants

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Pyrolysis of FeOx/g‐C3N4 and ZIF‐8 is performed to introduce Fe single atom and pyridinic nitrogen vacancies onto N‐doped carbon. This modification enables the materials to efficiently extract electrons from ciprofloxacin (CIP) and activate dissolved oxygen. 100% of CIP was degraded within 1 min without adding any oxidant.
Jianyang Gao, Ruonan Wang, Haifeng Lin, Jun Xing, Jixiang Xu, Lei Wang   +5 more
wiley   +1 more source

Assessing the influence of changes in land use-land cover on soil properties of degraded sodic lands in Indo-Gangetic plains. [PDF]

Sci Rep
Singh YP, Arora S, Mishra VK, Gupta RK.
europepmc   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Fortified farm yard manure to bio-stimulate nutrient availability and production of Indian mustard. [PDF]

PLoS One
Meena MK, Jat RS, Dotaniya ML, Meena MD, Meena V, Meena VS, Mawlong I, Choudhary RL, Singh H, Meena HS, Singh VV.   +10 more
europepmc   +1 more source

Sustained‐Release Ulcer‐Protective Microarray Patch With Dihydrocapsaicin for Diabetic Wound Regeneration

Exploration, EarlyView.
Schematic illustration of the effect of microneedles incorporating cerium‐based MOF loading dihydrocapsaicin (MN‐MOF@DHC) to scavenge reactive oxygen species (ROS) generation, beanti‐inflammatory, inhibit the apoptosis of endothelial cells (ECs), promote angiogenesis, and accelerate diabetic wound healing. ABSTRACT Diabetic foot ulcers (DFUs) present a
Yuxu Wu, Kan Jiang, Xiao Wen, Chihao Jin, Kai Zhang, Jiakai Zhang, Jiale Jin, Jiaqian Wang, Huiyu Hu, Zonghan Xu, Xianzhu Zhang, Yihe Hu   +11 more
wiley   +1 more source

A Comprehensive Review of the Biochar-Mediated Alleviation of Salt Stress. [PDF]

Plants (Basel)
Chandrasekaran M, Kang I, Ayyaru S, Kumar Alagarasan J, Sivanesan I.   +4 more
europepmc   +1 more source