Results 31 to 40 of about 977 (242)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Índices de calidad del agua subterránea para uso agrícola en el Soconusco, Chiapas, México

open access: yesEarth Sciences Research Journal, 2017
En el Soconusco, Chiapas, a pesar de la alta disponibilidad de agua superficial, se recurre al uso del agua subterránea. El conocimiento de la calidad del agua superficial o subterránea utilizada para el riego de los cultivos en la región es bajo.
Germán Santacruz de León   +4 more
doaj   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

open access: yesAdvanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu   +14 more
wiley   +1 more source

First National Report on Soil Salinity Across Paraguay

open access: yesTerra Digitalis, 2023
Assessing soil salinity on a national scale provides crucial information on soil fertility. Our objective was to map soil salinity in Paraguay at the topsoil layer (0-30 cm) using indicators such as Electrical Conductivity (EC), pH, and Exchangeable ...
Arnulfo Encina Rojas   +6 more
doaj   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

open access: yesAdvanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li   +9 more
wiley   +1 more source

Modeling salinity and sodicity risks under long-term irrigation with medium salinity water: Kinneret catchment as a case study

open access: yesAgricultural Water Management
Climate change is intensifying droughts and reducing freshwater availability in arid, semi-arid, and Mediterranean regions. Agricultural areas within the Lake Kinneret basin (Israel) are currently irrigated with high-quality Dan Spring water; however ...
Avishag Amouyal   +2 more
doaj   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre   +3 more
wiley   +1 more source

Soil degradation processes in the Italian agricultural and forest ecosystems

open access: yesItalian Journal of Agronomy, 2013
A number of processes of degradation threaten soil functions. Ten of them are acknowledged by the European Union and fifteen by the Organisation for Economic Co-operation and Development (OECD), but at least another seven have been indicated by different
Edoardo A.C. Costantini   +1 more
doaj   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou   +11 more
wiley   +1 more source

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