Results 31 to 40 of about 3,077 (239)

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Soil degradation processes in the Italian agricultural and forest ecosystems

Italian Journal of Agronomy, 2013
A number of processes of degradation threaten soil functions. Ten of them are acknowledged by the European Union and fifteen by the Organisation for Economic Co-operation and Development (OECD), but at least another seven have been indicated by different
Edoardo A.C. Costantini, Romina Lorenzetti   +1 more
doaj   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

Advanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li, Runzhe Huang, Qingyuan Wu, Pengbo Zhou, Dangli Ren, Jingjing Wang, Hanjie Niu, Zemeng Li, Hongtao Sun, Huiyu Liu   +9 more
wiley   +1 more source

The Integrated Amendment of Sodic-Saline Soils Using Biochar and Plant Growth-Promoting Rhizobacteria Enhances Maize (Zea mays L.) Resilience to Water Salinity

Plants, 2021
The utilization of low-quality water or slightly saline water in sodic-saline soil is a major global conundrum that severely impacts agricultural productivity and sustainability, particularly in arid and semiarid regions with limited freshwater resources.
Yasser Nehela, Yasser S. A. Mazrou, Tarek Alshaal, Asmaa M. S. Rady, Ahmed M. A. El-Sherif, Alaa El-Dein Omara, Ahmed M. Abd El-Monem, Emad M. Hafez   +7 more
doaj   +1 more source

Características químicas e salino-sodicidade dos solos do Perímetro Irrigado Califórnia, SE, Brasil Characteristcs chemical and soil salinization in the Irrigated District of California, SE, Brazil

Ciência Rural, 2007
O manejo inadequado da irrigação pode resultar no acúmulo de sais no solo, cuja intensidade depende da qualidade da água utilizada na irrigação, da fração de lixiviação adotada e da demanda evapotranspirativa da região.
Antenor de Oliveira Aguiar Netto, Carlos Clériston Santana Gomes, Carla Cristina Valois Lins, Allan Cunha Barros, Luis Fernando de Souza Magno Campeche, Flávio Favaro Blanco   +5 more
doaj   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Chemical characteristics of soil irrigated with produced water treatment and underground water

Dyna, 2019
Irrigation effects of produced water treatment, diluted in underground water, were analyzed through the chemical characteristics of argisol with foraging palm.
Danniely Oliveira Costa, Hudson Salatiel Marques Vale, Rafael Oliveira Batista, Kaline Dantas Travassos, Jeane Cruz Portela   +4 more
doaj   +1 more source

Improving Soil Physical Indicators by Soil Amendment to a Saline-Sodic Soil [PDF]

Desert, 2013
The application of organic amendments can be an appropriate solution to reclaim and improve physical propertiesof saline-sodic soils. In this research, an experiment was performed under greenhouse conditions to study the effect ofamendments to the ...
M. Khotabaei, H. Emami, A. Astaraei, A. Fotovat   +3 more
doaj   +1 more source

Pathological Copper Overload Reprograms SOD1 Activation via COMMD1 to Promote Senescence and Fibrosis

Advanced Science, EarlyView.
This study uncovers a previously unrecognized copper‐COMMD1‐SOD1 regulatory axis, revealing that pathological copper overload paradoxically suppresses SOD1 activity by promoting COMMD1‐dependent disruption of SOD1 homodimerization. These findings redefine the regulatory role of copper in SOD1 biology and provide novel mechanistic insight into the ...
Yuqing Liu, Jing Liu, Wenqian Zhou, Yangyang Niu, Yan Zheng, Yiguo Liu, Yingying Zhang, Chen Yu   +7 more
wiley   +1 more source