Results 141 to 150 of about 201,387 (263)

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

Advanced Science, EarlyView.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu, Xingyu Zhang, Jingjia Zhang, Gaohui Huang, Chen Zhou, Chunlin Li, Xiaojun Huang, Jianbo Xiao, Nianjie Feng, Yuanbin She   +9 more
wiley   +1 more source

Dietary management of pediatric patients with kidney disease: recommendations by the Korean Society of Pediatric Nephrology and the Korean Society of Clinical Nutrition. [PDF]

Clin Nutr Res
Ahn YH, Kang HG, Song J, Han S, Park E, Suh JS, Kim JY, Park MJ, Lee KH, Lim SH, Shin KH, Ko H, Lee HJ, Jeong E, Kim J, Park S, Choi E, Seo Y, Oh K, Kim JK, Lee HK.   +20 more
europepmc   +1 more source

Enzyme‐Activated MRI for In Vivo Glucose Imaging via a Biodegradable Chromium Nanoprobe

Advanced Science, EarlyView.
Enzyme‐activated MRI (eaMRI) using a biodegradable CrGOx@Lip nanoprobe enables glucose‐specific imaging in vivo. GOx catalyzes glucose oxidation, triggering in situ formation of paramagnetic chromium gluconate and amplifying T1. This radiation‐free strategy maps tumor glucose uptake via the Warburg‐effect, quantifies hepatic glucose accumulation in ...
Yan Xu, Weitao Yang, Yanjing Yun, Hui Wang, Zhuoyao Wu, Youyi Yu, Bingbo Zhang   +6 more
wiley   +1 more source

Interpretable Prediction of Late-Stage CKM Syndrome Association From Dietary Nutrients in Accelerated Aging Using SHAP and LIME. [PDF]

Food Sci Nutr
Tu H, Dai M, Zhu Y, Liang M, Shen M, Chen Y.   +5 more
europepmc   +1 more source

Are all meats substitutes? A basket‐and‐expenditure‐based approach

Agribusiness, EarlyView.
Abstract This study examines the relationship among animal‐based meat and plant‐based meat alternatives (PBMAs) using a basket‐and‐expenditure‐based choice experiment. In particular, we examine whether animal‐based meat products are substitutes or complements with PBMAs.
Clinton L. Neill, Logan L. Britton
wiley   +1 more source

Effect of Sodium Restriction on Cardiovascular Outcomes in Patients With Hypertension and Heart Failure: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Alqurain A, Al-Hasani OH, Alghamdi TA, Alsaadi J, Hakami AM, Alfahed NA, Hejazi YZ, Al-Hitawi QA, Asiri AM, Htaimesh GM, Mohamed AM, Alraddadi MS, Alqahtani MF, Metwaly AS, Alqurashi A.   +14 more
europepmc   +1 more source

Clinical utility of pharyngeal high‐resolution manometry with impedance for upper esophageal sphincter dysfunction in gastroenterology

Advances in Digestive Medicine, EarlyView.
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar, Taher Omari, Michal Szczesniak, Chien‐Lin Chen, Richard Heddle, Charles Cock   +5 more
wiley   +1 more source

Perspective: What is the Likely Impact of the Proposed Food and Drug Administration Front-of-Package Criteria on the Labeling of Foods? [PDF]

Curr Dev Nutr
Trumbo PR, Drewnowski A.
europepmc   +1 more source

More on dissidents and dietary sodium [PDF]

International Journal of Epidemiology, 2018
openaire   +2 more sources