Results 51 to 60 of about 5,928 (100)
, 2008 The work presented in this thesis describes the X-ray crystallographic studies of particulate methane monoxygenase (pMMO) from Methylococcus capsulatus (Bath), thioredoxin A (BsTrxA) from Bacillus subtilis and arginine decarboxylase (AdiA) from ...
Andrell, Juni, Andrell, Juni
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l-Lactate generates hydrogen peroxide in purified rat liver mitochondria due to the putative l-lactate oxidase localized in the intermembrane space [PDF]
, 1922 In order to ascertain whether and how mitochondria can produce hydrogen peroxide (H2O2) as a result of l-lactate addition, we monitored H2O2 generation in rat liver mitochondria and in submitochondrial fractions free of peroxisomal and cytosolic ...
de Bari, Lidia +3 more
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ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling
Advanced Science, Volume 13, Issue 16, 18 March 2026.ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao +19 more
wiley +1 more source
A substrate translocation trajectory in a cytoplasm-facing topological model of the monocarboxylate/H+ symporter Jen1p [PDF]
, 2011 Previous mutational analysis of Jen1p, a Saccharomyces cerevisiae monocarboxylate/H+ symporter of the Major Facilitator Superfamily, has suggested that the consensus sequence 379NXX[S/T]HX[S/T]QD387 in transmembrane segment VII (TMS-VII) is part of the ...
Abramson +31 more
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Advanced Science, Volume 13, Issue 16, 18 March 2026.This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding +7 more
wiley +1 more source
A cotton miRNA is involved in regulation of plant response to salt stress [PDF]
, 2016 The present study functionally identified a new microRNA (microRNA ovual line 5, miRNVL5) with its target gene GhCHR from cotton (Gossypium hirsutum). The sequence of miRNVL5 precursor is 104 nt long, with a well developed secondary structure.
AR Leitch +57 more
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MedComm, Volume 7, Issue 3, March 2026.Slc7a11‐mediated cystine uptake and glutathione synthesis inhibits M1 macrophage polarization by reducing Stat1 phosphorylation and markers expressions and promotes M2 macrophage polarization by enhancing Stat6 phosphorylation and markers expressions.
Shuaishuai Zhou +12 more
wiley +1 more source
Light-chain-induced renal tubular acidosis: effect of sodium bicarbonate on sodium-proton exchange [PDF]
, 2017 We measured sodium-proton (Na+/H+) exchange in lymphocytes and platelets of a 46-year-old woman with the adult Fanconi syndrome before, during, and after treatment with NaHCO3.
Luft, F. C. +4 more
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Medium alkalization due to carbon metabolism is largely responsible for inhibition of bacterial growth by Vibrio cholerae supernatants [PDF]
, 2017 Vibrio cholerae is the causative agent of the diarrheal disease cholera. Many Vibrio species secrete antimicrobial factors, though the identity of such a factor has not been determined for any V. cholerae strain.
Becker, Miranda
core +1 more source
Protein Science, Volume 35, Issue 3, March 2026.Abstract A key prerequisite of transporter proteins' function is their trafficking to the target cellular membranes where they fulfill distinct physiological roles. Cornichon proteins (CNIH/Erv14) represent a highly conserved family of coat protein complex II (COPII)‐coated vesicle cargo receptors that facilitate the exit of numerous transporters from ...
Karolína Kacovská +7 more
wiley +1 more source