Results 61 to 70 of about 5,928 (100)

Construction of targeting human Na(+)-H(+) exchanger-1 gene adenovirus-mediated RNA interference expression vector and establishment of intracellular acidification model

Chinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To construct adenovirus-mediated RNA interference (RNAi) expression vector of targeting human Na(+)-H(+) exchanger-1 (NHE-1) gene to infect SH-SY5Y cells and establish intracellular acidification model in order to lay the foundation for ...
Boyan FANG, Meifeng HUANG
doaj  

Proteomic identification of OsCYP2, a rice cyclophilin that confers salt tolerance in rice (Oryza sativa L.) seedlings when overexpressed [PDF]

, 2011
Background High Salinity is a major environmental stress influencing growth and development of rice. Comparative proteomic analysis of hybrid rice shoot proteins from Shanyou 10 seedlings, a salt-tolerant hybrid variety, and Liangyoupeijiu seedlings, a ...
Tong Jian-Xin, Wang Fang, Liu Wen-Zhen, Xin Ya, Fu Ya-Ping, Wang Shi-Heng, Ma Hua-Sheng, Ruan Song-Lin, Wang Shu-Zhen, Chen Hui-Zhe   +9 more
core   +2 more sources

The Rhus chinensis Genome Provides Insights Into Tannin, Flavonoid Biosynthesis, and Glandular Trichome Development

Plant Biotechnology Journal, Volume 24, Issue 3, Page 988-1013, March 2026.
ABSTRACT The “salt tree”, Rhus chinensis, holds significant economic and medicinal value due to its ability to produce Galla chinensis (Chinese gall/gallnut), a plant‐derived medicinal material used in both traditional Chinese and modern medicine that is rich in tannins and flavonoids. It is also renowned for its remarkable stress tolerance.
Zhaogeng Lu, Helin Zou, Jiawen Cui, Tongfei Wang, Lingyu Ma, Shixiong Ren, Yiwei Cao, Xi Zhang, Zixi Chen, Hongyan Bao, Ling Zhu, Yaning Cui, Ruili Li, Xiuyan Yang, Qikun Zhang, Zhili Wang, Wangxiang Zhang, Li Wang, Jinxing Lin, Biao Jin   +19 more
wiley   +1 more source

Characterization of a Basolateral Electroneutral Na+/H+ Antiporter in Atlantic Lobster (Homarus Americanus) Hepatopancreatic Epithelial Vesicles

, 1996
Purified basolateral membrane vesicles (BLMVs) were prepared from Atlantic lobster (Homarus americanus) hepatopancreas using a Percoll density gradient technique. Enrichments of the Na+/K+-ATPase and alkaline phosphatase activities of these vesicles were
Ahearn, Gregory A., Duerr, Jeff
core  

Exploring the directionality of Escherichia coli formate hydrogenlyase:a membrane-bound enzyme capable of fixing carbon dioxide to organic acid [PDF]

, 2016
During mixed‐acid fermentation Escherichia coli produces formate, which is initially excreted out the cell. Accumulation of formate, and dropping extracellular pH, leads to biosynthesis of the formate hydrogenlyase (FHL) complex. FHL consists of membrane
Andrews, Ashkenazy, Baba, Bagramyan, Bagramyan, Bagramyan, Bassegoda, Batista, Begg, Bettenbrock, Bowman, Brandt, Brandt, Brandt, Böhm, Casadaban, Deplanche, Doberenz, Efremov, Efremov, Efremov, Euro, Frielingsdorf, Guest, Hakobyan, Hamilton, Hedderich, Hirst, Kelley, Khangulov, Kim, Knappe, Krasna, Kuniyoshi, Laemmli, Lim, Maeda, Marreiros, McDowall, McDowall, Nguyen, Nitschke, Pakes, Peters, Pinske, Pinske, Pinske, Pinske, Ripple, Rittmann, Romano, Rossmann, Sapra, Sargent, Sauter, Sawers, Sawers, Sawers, Schlindwein, Schuchmann, Stephenson, Stephenson, Suppmann, Thauer, Towbin, Trchounian, Trchounian, Vignais, Wang, Weiss, Woods, Wu, Wyborn, Zhu, Zickermann   +74 more
core   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, Volume 13, Issue 12, 27 February 2026.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Molecular mechanism of ligand recognition by membrane transport protein, Mhp1 [PDF]

, 2014
The hydantoin transporter Mhp1 is a sodium-coupled secondary active transport protein of the nucleobase-cation-symport family and a member of the widespread 5-helix inverted repeat superfamily of transporters.
A Peter Johnson, Alexander D Cameron, Colin WG Fishwick, David Drew, David J Sharples, Ekaterina Ivanova, Florian Brueckner, Joseph Lanigan, Katie J Simmons, Mark SP Sansom, Oliver Beckstein, Peter JF Henderson, Scott M Jackson, Simon G Patching, Simone Weyand, So Iwata, Tian Geng, Zsoldos Z   +17 more
core   +4 more sources

Distinct Roles of SLC26A3 and CFTR in Surface pH Regulation and Bicarbonate Secretion in Human Intestinal Epithelium

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Background and Aims Colonic bicarbonate secretion is mediated by the chloride/bicarbonate exchanger SLC26A3 and the cystic fibrosis transmembrane conductance regulator (CFTR). Dysfunction of either causes luminal acidosis, altered mucus properties, and inflammation.
Mahdi Amiri, Azam Salari, Ursula Seidler
wiley   +1 more source

Multiple mechanisms mediate growth and survival in young seedlings of two populations of the halophyte Atriplex halimus (L) subjected to long single step salinity treatments [PDF]

, 2017
Understanding how halophytes survive high soil salinity in realistic long-term experiments is important for strategies to mitigate the effects of increasing soil salinity worldwide.
Arezki, Derridj, Hamdani, Faiza, Rogers, Hilary   +2 more
core   +1 more source

The genome of Pelobacter carbinolicus reveals surprising metabolic capabilities and physiological features [PDF]

, 2012
Background The bacterium Pelobacter carbinolicus is able to grow by fermentation, syntrophic hydrogen/formate transfer, or electron transfer to sulfur from short-chain alcohols, hydrogen or formate; it does not oxidize acetate and is not known to ferment
Cliff S Han, Derek R Lovley, Miriam L Land, Muktak Aklujkar, Olga Chertkov, Peter Brown, Raymond DiDonato, Shelley A Haveman   +7 more
core   +2 more sources