Results 251 to 260 of about 118,941 (325)

Sodium-glucose co-transporter 2 inhibitors: a pleiotropic drug in humans with promising results in cats. [PDF]

Front Vet Sci
Vieira AB, Cavanaugh SM, Ciambarella BT, Machado MV.   +3 more
europepmc   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

Advanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen, Xiaoteng Cui, Xinyi Shi, Xu Yang, Yujing Cao, Haolin LI, Qi Zhan, Qixue Wang, Ang Li, Qihong Cheng, Yunfei Wang, Junhu Zhou, MingJie Wang, Chunsheng Kang, Xiaomin Liu   +14 more
wiley   +1 more source

Effects of sodium-glucose co-transporter-2 inhibitors on the risk of nephrolithiasis and urinary tract infections in Thai patients with type 2 diabetes: a hospital-based cohort study. [PDF]

Diabetol Metab Syndr
Lukkunaprasit T, Tansawet A, Siriyotha S, Looareesuwan P, Yang J, Kunakorntham P, Sirisreetreerux P, Anothaisintawee T, McKay GJ, Attia J, Thakkinstian A.   +10 more
europepmc   +1 more source

Cell Cycle‐Specific Regulation of Centrosome Clustering Dynamics in Cancer Cells by the Multifunctional Kinesin HSET

Advanced Science, EarlyView.
CDK5RAP2 associates with the kinesin HSET and forms co‐condensates. HSET motors drive the directional transport of CDK5RAP2 condensates toward microtubule minus ends. During mitosis, HSET self‐assembly further stabilizes clustered centrosomes, thereby enabling pseudo‐bipolar spindle formation in cancer cells with supernumerary centrosomes. Upon mitotic
Po‐Pang Chen, Athira Saju, Chia‐Chou Wu, Tzu‐Han Weng, Su‐Yi Tsai, Tzu‐Lun Huang, Jia‐Ying Su, Chien‐Ling Lin, Yu‐Chun Lin, See‐Yeun Ting, Sheng‐hong Chen, Kuo‐Chiang Hsia   +11 more
wiley   +1 more source

The clinical efficacy and safety of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in patients with acute myocardial infarction: a meta-analysis of randomized controlled trials. [PDF]

Ann Med Surg (Lond)
Khan MS, Hashmi TM, Jehangir H, Akram MF, Munawar I, Jagani SD, Maqsood M, Khalid A, Ijaz M, Saeed U, Jafar U, Ehsan M, Tuglo LS, Rehman WU, Sabouni MA, Braiteh N, Yarkoni A, Patel K.   +17 more
europepmc   +1 more source

Unlocking Plant‐Derived Potential: Regulating Microcrystalline Structure Design of High‐performance Hard Carbon Anodes via Cellulose Molecules

Advanced Science, EarlyView.
The microcrystalline structure of hard carbon derived from green sandalwood is modulated by controlling the steric hindrance effect of the precursor, thereby significantly enhancing ion diffusion kinetics. When utilized in sodium‐ion batteries, it demonstrates excellent cycle life, exceeding 7000 cycles, as well as superior low‐temperature performance,
Xiping Zhang, Wenhao Yang, Dan You, Ziyi Zhu, Xue Li   +4 more
wiley   +1 more source

Sodium-glucose co-transporter 2 inhibitors use and the risks of genital and urinary tract infection: What should we know? [PDF]

Tzu Chi Med J
Wu DA, Hsu BG, Lin YL.
europepmc   +1 more source

Poria cocos as a Functional Food for Diabetes and Diabetes‐Related Foot Ulcers

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Poria cocos is known as an edible mushroom for food and medicine. Poria cocos and its terpenes and terpenoids serve as novel remedies to treat diabetes and its ulcers. Its mode of actions includes reduction of insulin resistance, starch digestion and inflammation as well as promotion of blood vessel formation. ABSTRACT Poria cocos is a medicinal fungus
Yi‐San Lee, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +3 more
wiley   +1 more source

Sodium-glucose co-transporter 2 inhibitors improve insulin resistance and β-cell function in type 2 diabetes: A meta-analysis. [PDF]

World J Diabetes
Chai SY, Zhang RY, Ning ZY, Zheng YM, Swapnil R, Ji LN.   +5 more
europepmc   +1 more source